قسم المختبرات الطبية

قسم المختبرات الطبية

أ/ التخصصات :

وتشمل ثلاثة تخصصات رئيسية وهي الكيمياء السريرية والأحياء الدقيقة وأمراض الدم بالإضافة لتخصصين فرعيين هما الأنسجة المريضة والطفيليات الطبية

ب/ المكاتب : وتشمل

ج/ القاعات وتشمل

د/ المعامل : وتشمل

بسم الله الرحمن الرحيم

جامعة الشيخ عبد الله البدري

كلية العلــوم الصحية

مقترح منهج بكلاريوس المختبرات الطبية المنقح

(درجة الشرف)

مقدمة

خلفية تاريخية:

في سنة 2007م أنشأ الشيخ عبد الله البدري كلية تقنية صحية بلغت مساحة أبنيتها 1800 متر مربع مستهدفة توفير كوادر طبية مساعدة تمنح درجة الدبلوم التقني في تخصصات (التمريض – الصيدلة – الإحصاء الطبي – مساعدي طب الأسنان) وابتدأت الدراسة فيها في عام 2008 م، وتم افتتاحها في يناير 2009م.

تم إقتراح إضافة برنامج علوم المختبرات الطبية (بكالوريوس عام) إلى برامج الكلية من قبل مجلس الأساتذة بالجامعة ومن ثم مجلس الجامعة نسبة لحوجة الولاية الشديدة لتلك الكوادر في مجال المختبرات الطبية ووجود إقبال عالي من الطلاب على تلك البرامج فكان لابد من التجهيز لقيام هذا البرنامج، وقد تم بحمد الله استجلاب عدد مقدر من الأجهزة والمعدات الطبية الخاصة بهذا البرنامج من خارج السودان (الصين) على نفقة الشيخ عبد الله البدري. وبالفعل تم قبول أول دفعه في العام 2013م. بعدد 60 طالبا وطالبه قبول عام و30 طالب قبول خاص واستمر التطور في استكمال البنية التحتية للقسم وتوالي القبول لدفعتين جديدتين عامي 2014 -2015 بتلك الأعداد المقدرة فكان لزاما أن يتبع هذا التطور المطرد من أجهزه ومعدات ومعامل تطور في مفردات المناهج تماشيا ومواكبه لكل ما هوجديد.

تم تنقيح منهج المختبرات بواسطة لجنه من أهل الاختصاص لتتم إضافة بعض المواد المهمة التي تساعد الطالب على فهم المواد التخصصية مثل مواد مدخل لعلم الأدوية والمضادات الحيوية-طب المجتمع وعلم الوبائيات – بعض التقنيات المهمة لمعامل الطب الشرعي – علم الإحصاء الحيوي بالإضافة إلى تعديل بعض عناوين المحاضرات تبعا للبحوث والمعلومات العلمية المنشورة حديثا. مما زاد عدد الساعات المعتمدة من 152فى الخطة المعتمدة إلى 166 ساعة معتمده وعليه يمنح البرنامج بكالوريوس الشرف في علوم المختبرات الطبية بدلا من بكالوريوس عام. كما اقترحت اللجنة أن يتخرج الطالب في السنة النهائية بتخصصين لاتجاه معظم العلوم الطبية والصحية للتخصصية وأسوة بنظيراتها من الكليات بالجامعات السودانية والعالمية.

ملخص توصيات اللجنة:

  1. اعتماد المقررات المضافة للخطة الدراسية بساعاتها المعتمدة.
  2. اعتماد تخرج الطالب ببكالوريوس درجة الشرف بدلا عن البكلاريوس العام بناءا على زيادة الساعات المعتمدة.
  3. اعتماد تعديل بعض عناوين المحاضرات.
  4. اعتماد مقترح تخرج الطالب في السنة النهائية بتخصصين.
  5. يتم اختيار مادتي التخصص وفقا للشروط والمعدلات في السنة النهائية بمجموع 19ساعة معتمدة في الفصل الدراسي السابع و14ساعة معتمدة في الفصل الدراسي الثامن

 تشكيل اللجنة:

تشكلت اللجنة التي نقحت هذا المنهج من الأساتذة:

  1. أ.د البدري الأمين محمد – تخصص علم الطفيليات                                     رئيسا
  2. د. فانيا عبد الله البدري – الطب والجراحة – تخصص النساء والتوليد             عضوا
  3. د. عبد الله ميرغني دياب – الطب والجراحة – تخصص الطب الشرعي           عضوا
  4. د. الواثق يحى محمد نور – الطب والجراحة – تخصص طب المجتمع            عضوا
  5. د. مرتضى عثمان الطاهر – الطب والجراحة – تخصص طب المجتمع           عضوا
  6. د. محمد محجوب الحسن – مختبرات طبيه – تخصص الكيمياء السريرية       عضوا
  7. د. إبراهيم بخيت     – مختبرات طبيه – تخصص الأنسجة                          عضوا
  8. أ. حسام على عثمان – مختبرات طبيه – تخصص أمراض الدم                    عضوا
  9. أ. محمد عبد الرحمن سيد – مختبرات طبيه – تخصص أمراض الدم             عضوا
  10. أ. بابكر محمود عثمان – مختبرات طبيه – تخصص الأحياء الدقيقة              عضوا
  11. أ. هشام عبد الحميد ابن إدريس – مختبرات طبيه – تخصص علم المناعة      عضوا

Semester 1

الخطة المنقحة

 CodeCourseCredit hours
1.1.1MLS-ANTAnatomy2(1+2)
1.1.2MLS.ARBArabic language-13(3+0)
1.1.3MLS. CHMGeneral  Chemistry3(2+1)
1.1.4MLS.CSComputer sciences3(2+3)
1.1.5MLS.ENGEnglish language-13(3+0)
1.1.6MLS.ISCIslamic culture-13(3+0)
1.1.7MLS.PHCMedical physics2(1+2)
1.1.8MLS-PHYPhysiology-12(1+2)
1.1.9MLS-IM LIntroduction to medical laboratory2(1+2)
1.1.10MLS-SUDSudanese Studies3(3+0)
Total26

Semester 2

الخطة المنقحة

 CodeCourseCredit hours 
1.2.1MLS-N HNormal histology3(2+3) 
1.2.2MLS.ARBArabic language-23(3+0) 
1.2.3MLS. PHYPhysiology-22(1+2) 
1.2.4MLS.INSInstrumentation3(2+3) 
1.2.5MLS.ISCIslamic culture-23(3+0) 
1.2.6MLS.ENGEnglish language-23(3+0) 
1.2.7MLS.BILBiology2(1+2) 
1.2.8MLS. BIOBiochemistry2(1+2) 
1.2.9MLS.LABlaboratory  safety2(1+2) 
Total23

Semester 3

الخطة المنقحة

 CodeCourseCredit hours
2.3.1MLS- MIC-231Microbiology-13(2+3)
2.3.2MLS-CCH-232Clinical chemistry-13(2+3)
2.3.3MLS-HEM-233Haematology-13(2+3)
2.3.4MLS-PAR-234Parasitology-13(2+3)
2.3.5MLS-HIS-235Histopathology-13(2+3)
2.3.6MLS-IMM-236Basic immunology3(2+3)
2.3.7MLS.COH-237Community Health2(2+0)
Total20

Semester 4

الخطة المنقحة

 CodeCourseCredit hours
2.4.1MLS-MIC-241Microbiology-23(2+3)
2.4.2MLS-CCH-242Clinical chemistry-23(2+3)
2.4.3MLS-HEM-243Hematology -23(2+3)
2.4.4MLS.HIS-244Histopathology -23(2+3)
2.4.5MLS-PAR-245Parasitology-23(2+3)
2.4.6MLS.PAT-246General Pathology2(2+0)
2.4.7MLS.EPD-247Epidemiology2(2+0)
Total19

Semester 5

الخطة المنقحة

 CodeCourseCredit hours
3.5.1MLS-MIC-351Microbiology -33(2+3)
3.5.2MLS-CCH-352Clinical  Chemistry -33(2+3)
3.5.3MLS-CIM-353Clinical immunology3(3+0)
3.5.4MLS-HEM-354Hematology-33(2+3)
3.5.5MLS-MOB-355Molecular biology-12(1+2)
3.5.6MLS.HIS-356Histopathology-33(2+3)
3.5.7MLS-PAR-357Parasitology-33(2+3)
Total20

Semester 6

الخطة المنقحة

 CodeCourseCredit hours
3.6.1MLS-MIC-361Microbiology -43(2+3)
3.6.2MLS-CCH-362Clinical  Chemistry -43(2+3)
3.6.3MLS-PAR-363Parasitology-43(2+3)
3.6.4MLS-HEM-364Hematology-43(2+3)
3.6.5MLS-HIS-365Histopathology-43(2+3)
3.6.6MLS-QCL-366Laboratory management & Quality assurance3(3+0)
3.6.7MLS-PHA-367Pharmacology2(2+0)
  In-Service Training3(0+6)
Total23

Semester 7

الخطة المنقحة

 CodeCourseCredit hours
4.7.1MLS-CCH-471Clinical Chemistry-54(3+3)
  Elective course (Histopathology or Parasitology)4(3+3)
4.7.2MLS-RM-472Research Methodology2(2+0)
4.7.3MLS-GEN-473Genetics3(3+0)
4.7.4MLS-FOR-474Forensic laboratory2(2+0)
4.7.5MLS.MOB-475Molecular biology-22(2+1)
  In-Service Training3(0+6)
Total20
 CodeCourseCredit hours
4.7.3MLS-HEM-476Hematology -54(3+3)
  Elective course (Histopathology or Parasitology)4(3+3)
4.7.2MLS-RM-472Research Methodology2(2+0)
4.7.3MLS-GEN-473Genetics3(2+3)
4.7.4MLS-FOR-474Forensic laboratory  2(2+0)
4.7.5MLS. MOB-475Molecular biology-22(2+1)
  In-Service Training3(0+6)
Total20
 CodeCourseCredit hours
4.7.3MLS-MIC-478Microbiology -54(3+3)
  Elective course (Histopathology or Parasitology)4(3+3)
4.7.2MLS-RM-472Research Methodology2(2+0)
4.7.3MLS-GEN-473Genetics 3(2+3)
4.7.4MLS-FOR-474Forensic laboratory  2(2+0)
4.7.5MLS. MOB-475Molecular biology-22(2+1)
  In-Service Training3(0+6)
Total20

Semester 8

الخطة المنقحة

 CodeCourseCredit hours
4.8.1MLS-DHEM-481Diagnostic Hematology4(3+3)
  Elective course (Histopathology or Parasitology)4(3+3)
  Graduation project3(6+0)
  In-Service Training3(0+6)
4.8.2MLS-BIS-482Biostatistics2(1+2)
4.8.3MLS- M ET-483Medical Ethics2(2+0)
Total18
 CodeCourseCredit hours
4.8.3MLS-DMIC-483Diagnostic Microbiology4(3+3)
  Elective course (Histopathology or Parasitology)4(3+3)
  Graduation project3(6+0)
  In-service training3(3+6)
4.8.2MLS-BIS-482Biostatistics2(1+2)
4.8.3MLS- M ET-483Medical Ethics2(2+0)
Total18
 CodeCourseCredit hours
4.8.6MLS-DCCH-486Diagnostic Clinical chemistry4(3+3)
  Elective course (Histopathology or Parasitology)4(3+3)
  Graduation project3(6+0)
  In-service training3(3+6)
4.8.2MLS-BIS-482Biostatistics2(1+2)
4.8.3MLS- M ET-483Medical Ethics2(2+0)
Total18

الموضوع
رقم الصفحة
جدول مقررات الخطة المجازة3
جدول مقررات الخطة المنقحة6
3- وصف مقررات المنهج للفصل الدراسي الأول12
4- وصف مقررات المنهج للفصل الدراسي الثاني34
5- وصف مقررات المنهج للفصل الدراسى الثالث50
6- وصف مقررات المنهج للفصل الدراسى الرابع66
7- وصف مقررات المنهج للفصل الدراسى الخامس80
8- وصف مقررات المنهج للفصل الدراسى السادس95
9- وصف مقررات المنهج للفصل الدراسى السابع109
10- وصف مقررات المنهج للفصل الدراسى الثامن133

الفصل الدراسي الأول

ANATOMY

Titles of the course: ANATOMY   

Intended term: term (1)

Course duration: 15 weeks

Lectures: 2 hours per week – Duration 15 weeks

Practical: 3 hours per week – Duration 15 weeks

Credit hours: 2

Rationale

This course is intended for medical laboratory science students

General objective

By the end of this course, medical laboratory student should be able to:

1- Know the general anatomical and histological terminology & construction of the human body.

2- Understand the major properties and morphology of bones, muscles, vessels, nerves, and other tissue.

Specific objective

At the end of this course, medical laboratory students should be able to:

1- Know the basic units of the human skeleton, joints, muscles, blood vessels, and lymphatic.

2- Understand the construction of the human body systems, e.g. respiratory, blood circulation, genito-urinary, gastro-intestinal, nervous, endocrine, and lymphatic systems.

3- Know the histological details of the human tissues, e.g. cells, epithelia, supporting tissue, nervous tissue, muscular tissues, and gastro-intestinal urinary tissue.

Instructional methods

Evaluation

Final examinations run by internal examiners


Course contents

The course covers the following subjects

Lectures

Week (1)

 Anatomy of the musculo-skeletal system.

 Human skeleton

Week (2)

Muscular system

Week (3)

          Anatomy of the cardio – vascular system

Week (4)

        Anatomy of the lymphatic system

Week (5)

Anatomy of the respiratory system

Week (6)

Anatomy of the gastro – intestinal tract

Week (7) 

Anatomy of the urinary system

Week (8) 

Anatomy of the reproductive system

Week (9)

Anatomy of the nervous system

Week (10)

Anatomy of the endocrine system

Week (11)

          Cartilage

Hyaline & elastic cartilage

White fibro cartilage

Week (12)

 bone

Compact bone

Week (13)

Chancellors bone & Ossification bone

Week (14) 

Revision

Week (15)  

Class Test

Practical sessions

Week (1) Anatomy of musculo – skeletal system

Week (2) Anatomy of cardiovascular & lymphatic system

Week (3) Anatomy of respiratory system & gastrointestinal tract

Week (4) Anatomy of urinary & reproductive systems

Week (5) Anatomy of nervous & endocrine systems

Week (6) white fibrous connective tissue plus hyaline & elastic fibro – cartilage

Week (7) Bone, ground, decalcified, compact, growing, spongy bones

Week (8) Transverse & longitudinal sections of skeletal muscles

Week (9) Histology of cardiac and valves

Week (10) Nervous tissue nerve trunk, and ganglion ‘spinal sympathetic

Week (11) Histology of skin: tip of finger & scalp

Week (12) Histology of aorta, basilar and coronary arteries

Week (13) Histology of arteries veins

Week (14) Lymphatic tissue: lymph node, spleen, tonsil and thymus

Week (15) Histology of trachea & lung “adult & fetal”

  اللغة العربية -1

الأولي

الفترة الزمنية للمنهج: 15 أسبوع

المحاضرات: ساعتان في الأسبوع ولمدة 15 اسبوع

عدد الساعات المعتمدة: 3 ساعات

الطلاب المعنيون: طلاب علوم المختبرات الطبية

الأهداف العامة للمنهج

عند إتمام دراسة المنهج ينبغي أن يكون الطالب قادراً على:

1-معرفة الأسس والمفاهيم العلمية التي تساعد الطالب في الاستفادة من المراجع العلمية المكتوبة باللغة الإنجليزية.

2-الإسهام بصورة فعالة في سياسات التعليم العالي بدفع عجلة التعريب.

الأهداف الخاصة للمنهج

عند إتمام دراسة المنهج ينبغي أن يكون الطالب قادراً على:

1- معرفة حقيقة اللغة ونشأتها ومعالجة الاخطاء الشائعة بين الطلاب .

2- الإلمام بصياغة المصطلح العلمي ووضعه من المصادر المختلفة .

3- معرفة بعض العلوم المساعدة في وضع المصطلح العلمي كالنحت والإشتقاق .

4- الإلمام بقواعد واساسيات الترجمة والتعريب .

5- معرفة المستويات اللغوية والإختلاف بين الإنجليزية والعربية في النبر .

محتويات المنهج

المحاضرات

الأسبوع الأول :حقيقة اللغة ونشأتها

الأسبوع الثاني : الفرق بين اللغة وعلم اللغة

الأسبوع الثالث : نافذة علي اللغة : معالجة الأخطاء الشائعة وسط الطلاب

الأسبوع الرابع : أساليب الكلام : الإيجاز والإطناب والمساواة

الأسبوع الخامس : الترقيم : الأغراض

الأسبوع السادس : الترقيم : علاماته واستخداماتها

الأسبوع السابع : المصطلح العلمي : قوانين صياغة المصطلح العلمي

الأسبوع الثامن : وضع المصطلح العلمي من التراث

الأسبوع التاسع : وضع المصطلح العلمي من الطرق المتعددة لتوليد الألفاظ

الأسبوع العاشر : وضع المصطلح من الصياغة العربية للعرب والدخيل

الأسبوع الحادي عشر : وضع المصطلح العلمي من الجهود المبذولة من قبل العلماء

الأسبوع الثاني عشر : الاشتقاق وتعريفه تقسيم اللغات حول الاشتقاق

الأسبوع الثالث عشر : أصل الاشتقاق

الأسبوع الرابع عشر : أنواع الاشتقاق

الأسبوع الخامس عشر : النحت : تعريفه ، رأي الباحثين

General Chemistry

TITLE OF THE COURSE: General and Organic Chemistry

Intended term : term (1)

Course duration : 15 weeks

Lectures: 2hrs /week duration 15 week

Credit hours : 3 hours

GENERAL OBJECTIVES:

At the end of the course student should be able:

1. To understand the principle behind biochemical laboratory techniques.

2. Make a correct calculation of results.

3. Standardized solution, Identify organic compounds and be aware of their

Properties and reactions.

COURSE DESCRIPTION:

The course covers the following subjects:

1. General chemistry including chemical compounds, simple principles on what chemical analysis is based.

2. Organic chemistry nomenclature, structure, and properties.

3. Chemistry related to biochemical functions in the human body.

COURSE CONTENTS:

The course covers the following topics:

1. Introduction, including chemical terminology:

2. Simple principles on which chemical analysis is based, including:

3. Organic chemistry including:


Introduction to computer sciences

Title of the course: Computer sciences

Intended term: Term (1)

Course duration: 15 Weeks

Lectures: 2 hours per week – Duration 15 weeks

Practical : 3 hours per week – Duration 15 weeks

Credit hours : 3 hours per week

Rationale

This course is intended for medical laboratory science students .

General Objective

By the end of this course, medical laboratory should be able to :

  1. Know the types, functions and commands of computer software as well as and principles of DOS, data base, lotus, excel and windows.
  2. Understand the bases of Microsoft word sorting, planning, tools and applications.
  3. Know the principles of statistical analysis, spread sheet and technical writing.

Specific Objective

At the end of this course, medical laboratory students should be able to:

  1. Know the components, electrical aspects, languages and applications of computer.
  2. Understand the definition types and functions of software as well as, the principles of DOS system regarding commands and syntax.
  3. Know types, versions, files creation, entry and sorting of data for data base program.
  4. Know how to apply Lotus, Excel and Windows techniques .
  5. Know the planning sorting, insertion , and tools of Microsoft word , in addition to initiation of tables and insertion of pictures .
  6. Understand the types and applications of statistical analysis, spread sheet and writing techniques.

Instructional methods

Evaluation

Final examinations run by internal examiners

Evaluation consist of

Course contents

The course covers the following subjects :

Lecture

Week (1) Introduction to computer

Week (2) Computer software

Week (3) DOS system

Week (4) Data base

Week (5) Data base III

Week (6) Lotus 123

Week (7) Excel

Week (8) Windows

Week (9) Microsoft word-1

Week (10) Microsoft word-2

Week (11) Microsoft word-3

Week (12) introduction to statistical analysis

Week (13) Spread sheet

Week (14) Statistical analysis of data using spread sheet

Week (15) Technical writing

Practical applications

Week (1) introductory practical

Week (2) DOS-1

Week (3) DOS-2

Week (4) Data base III-1

Week (5) Data base III-2

Week (6) Windows application-1

Week (7) Windows application-2

Week (8) Windows application-3

Week (9) Excel-1

Week (10) Excel-2

Week (11) Microsoft word-1

Week (12) Microsoft word-2

Week (13) Spread sheet-1

Week (14) Spread sheet-2

Week (15) Technical writing

ENGLISH LANGUAGE -1

Title of the course: Scientific English (1)

Intended term : term (1)

Course duration : 15 weeks

Lectures : 2 hours per week

Duration : 15 weeks

Credit hours : 3 hours per week

Rationale

This course is intended for medical laboratory science students

General Objective

By the end of this course, medical laboratory students should be able to:

  1. Know how to write and speak English fluently

Specific Objective

  1. Know the root,suffix and prefix and their combination on between these items and syntax used in scientific writings.
  2. Understand the scientific medical term.
  3. Know the use of miscellaneous syntax scientific writings.

Instructional methods

Evaluation

1. Final examinations run by internal examiners

2. Evaluation consists of:

Course contents

The course covers the following subjects:

  1. Lectures

Week (1) :

Introduction to medical terminology

Week (2) :

Root and counting term

Week (3):

Prefix

Week (4):

Suffix

Week (5):

Body parts – root word

Week (6):

Abbreviation and pronunciation

Week (7)

Diseases and diagnosis suffix

Week (8)

Case study

Week (9)

Root word

Week (10)

Analysis of medical term

Week (11)

Common suffix and prefix

Week (12)

Revision

Week (13) Test

الثقافة الإسلامية -1

اسم المنهج : الثقافة الإسلامية

الفترة الدراسية : الفترة الأول

الفترة الزمنية للمنهج : 15 أسبوع

المحاضرات : ساعتان في الأسبوع ولمدة 15 أسبوع

عدد الساعات المعتمدة : 3 ساعات

الأهداف العامة للمنهج

عند إتمام دراسة المنهج ينبغي أن يكون الطالب قادراً علي :

  1. التعرف علي أهمية الأخلاق والعلم والإيمان في الحياة .
  2. التعرف على رأي الإسلام في المستجدات الحديثة ودور تقني المختبرات الطبية في المجتمع الإسلامي

الأهداف الخاصة للمنهج عند إتمام دراسة المنهج ينبغي أن يكون الطالب قادراً علي:

  1. معرفة فقه الجنائز والتعرف الديني للموت مقروناً مع علم التشريح .
  2. معرفة الموقف الفقهي والرأي الديني من نقل وزراعة الأعضاء ، نقل الدم ، منع الحمل والإجهاض والتلقيح الاصطناعي .

محتويات المنهج

الأسبوع الأول : الإيمان والعقل والعلم والعمل

 الأسبوع الثاني : مفهوم الأخلاق في الإسلام وأهميتها في الحياة الإنسانية

الأسبوع الثالث : أهمية الأخلاق في ممارسة المهن الطبية المختلفة

الأسبوع الرابع : مواصفات المسلم الذي يعمل في مجالات المهن الطبية المختلفة

الأسبوع الخامس : التعرف بالموت والمفهوم الديني والسكتة الدماغية

الأسبوع السادس : الاحتضار ، تلقين الشهادة ، غسل الميت وصلاة الجنازة

الأسبوع السابع : تعريف علم التشريح وأغراضه

الأسبوع الثامن : إسهامات الثقافة الإسلامية في علم التشريح

الأسبوع التاسع : نظرة الإسلام إلي نقل وزراعة الأعضاء

الأسبوع العاشر : الموقف الفقهي من نقل الدم

الأسبوع الحادي عشر : موقف الشريعة الإسلامية من الإجهاض

الأسبوع الثاني عشر : رأي الدين في وسائل منع الحمل وتنظيم الأسرة

الأسبوع الثالث عشر : الموقف الفقهي من التلقيح الاصطناعي بأنواعه المختلفة

الأسبوع الرابع عشر : رأي الدين في أطفال الأنابيب

الأسبوع الخامس عشر : دور تقني المختبرات الطبية في المجتمع الإسلامي

Medical Physics

Intended term: (1)

Course duration: 15 weeks

Lectures: 2 hours per week – duration 15 week

Practical: 3 hours per week – duration 15 week

Credit hours: 2 hours per week

Rationale

This course is intended for medical laboratory science students

General Objectives

By the end of this course medical laboratory students should be able to:

1. Know the principles of mechanics, optics, temperature measurement and basic calorimetric.

2. Understand the properties of matter and other physical parameters related to medical physics.

Specific Objectives

At the end of this course, the students should be able to:

  1. Know the units and dimensions plus dimensional analysis.
  2. Understand the properties of matter, fluid flow, friction, surface tent ion, and oscillatory motion.
  3. Understand the principles of wave phenomena and optics.
  4. Know the principles of temperatures measurement and calorimetry.
  5. Know kinetic theory, bases of elctrostatistics& introduction to electronics.

Instructional methods

Evaluation

Final examinations run by internal examiners and consist of the following:

Course contents   

The course covers the following subjects:

Lectures

Week (1) Mechanics 

Week (2) Elastic properties of matter

Week (3) Fluid flow

Week (4) Friction

Week (5) Surface tension

Week (6) Oscillatory motion

Week (7) Wave phenomena

Week (8) Optics

Week (9) temperature measurement

Week (10) Calorimetry

Week (11) Kinetic theory

Week (12) Electro statistics

Week (13) introduction to electronics

Week (14) junction diode characteristics

Week (15) bipolar transistor characteristics

Practical courses

Week (1) Simple pendulum

Week (2) Measurement of surface tent ion

Week (3) Determination of acceleration due to gravity

Week (4) Realization of Hoke’ principle

Week (5) Ohm’s law confirmation

Week (6) Gauss’s law in magnetism

Week (7) Boil’s law of pressor

Week (8) Determination of velocity of sound by Reasonalt tubes

Week (9) Determination of refraction index-1

Week (10) Determination of refraction index-2

Week (11) Determination of Focal length

Week (12) Young coefficient

Week (13) Internal resistant measurement

Week (14) Determination of voltmeter resistance by the simple method

Week (15) Frequency determination of power supply alternative current by son meter

Physiology -1

Course title: Physiology

Intended term: (1)

Course duration: 15 weeks

Lectures: 2 hours per week (30 hours)

Credit hour: 2 hours

Rationale:

This course is intended for medical laboratory science students.

Course description:

This course provides a basic background to the principal physiological systems of the human body, includes the blood autonomic nervous, cardiovascular, respiratory, gastrointestinal, endocrine, renal and central nervous system.

General Objectives:

By the end of this course, medical laboratory science students should:

1- State the role of the different body systems in regulating the internal environment.

2- Integrate information about various body systems and describe how one system impacts the other systems.

3- Given a description of an abnormality in a body system , students should be able to predict how this will affect homeostasis and how the body will attempt to compensate for the abnormality .

Specific Objectives:

 At the end of this course, the students should be able to:

1- Know the physiology of body fluids and their measurement.

2- Know the physiology of the blood, know the functions and physical characteristics of blood and know the physiology of the red cells, white cells & platelets.

3- Know the physiological basis of cardiac muscle, the vascular system, breathing gas exchange, lung volume, and lung capacity.

4- Know the composition and function of GIT hormones, gastric movement saliva, gastric juice, pancreatic secretion and bile.

5- Understand the types, structures, function and control of neuro-hormones, growth hormone, posterior pituitary hormones, thyroid hormones, and pancreatic hormones.

6- Understand the physiology renal clearance, renal circulation, counter-current mechanism, acid-base balance, and maturation disturbances.

7- Know the physiology of the sensory system reflexes, and motor mechanisms.

Instructional methods

Evaluation

Evaluation consists of:

Resources:

Lecture room, computer and multimedia projector

Course Content :

Week’s        lectures

First semester

1- Introduction of human physiology

2- Introduction of human physiology

3- Introduction of human physiology

4- Introduction of human physiology

5- Introduction of human physiology

6- The Blood

7- Red blood cell

8- White blood cell and the basis of immunity

9- Platelets   – Haemostasis

10- The Autonomic Nervous System

11- The Autonomic Nervous System

12- Cardiovascular System

13-  Cardiovascular System

14- Cardiovascular System

15- Cardiovascular System

The systemic circulation

Introduction to Medical Laboratory

TITLE OF THE COURSE: Introduction to Medical Laboratory

Intedend term : term (1)

Course duration : 15 weeks

Lectures : 2 hours per week

Credit hours : 2 hours

COURSE DESCRIPTION:

The course covers the following topics:

1.       Lectures

Week (1):

Introduction and historical background

Week (2):

Regulatory and responsibilities & organization of laboratories

Week (3):

Role of clinical laboratories in diagnosis of diseases

Week (4):

General safety procedures for employers & patients

Week (5)

Specimen types- collection-storage – transport

Week (6):

Patient preparation and special condition

Week (7):

Laboratory ware and main devices

Week (8)

Metric system and basic calculation methods

Week (9)

Laboratory designation

Week (10)

 Criteria of good laboratory designation

Week (11)

Analysis and recording of laboratory results

Week (12)

 Revision

Week (13)

Tutorial

Week (14)

Class Test

الدراسات السودانية

اسم المنهج : دراسات سودانيه

الفترة الدراسية : الفصل الدراسي الأول

الفترة الزمنية للمنهج : 15 أسبوع

المحاضرات : ساعتان في الأسبوع ولمدة 15 أسبوع

عدد الساعات المعتمدة : 3 ساعات

الأهداف العامة للمنهج

1- تعريف الطالب بأصول الثقافة السودانية وهويتها عربيا وأفريقيا.

2- معرفة التطور التاريخي للدولة السودانية.

3- معرفة القبائل السودانيه وتنوعها.

4- معرفة عوامل الوحدهالوطنيه.

محتويات المنهج

الأسبوع الأول :الثقافه السودانيه

الأسبوع الثاني : التنوع الثقافى واثره علي هوية السودان

الأسبوع الثالث :اصول القبائل العربيه

الأسبوع الرابع : الحضارات السودانيه عبر القرون

الأسبوع الخامس : القبائل السودانيه

الأسبوع السادس : النشاط الاقتصادىفى السودان

الأسبوع السابع :الهجره الداخليه والخارجيه

الأسبوع الثامن : سمنار

الأسبوع التاسع : العادات الضارة في المجتمع السودانى

الأسبوع العاشر : عوامل الوحدة الوطنية

الأسبوع الحادي عشر : تطور نظام الحكم فى السودان

الأسبوع الثاني عشر : سمنار

الأسبوع الثالث عشر : سياسة الدولة المهدية واثرها فى الحياة الاجتماعيه

الأسبوع الرابع عشر :  الحياة الاجتماعية في عهد الخليفه عبدالله التعايشى

الأسبوع الخامس عشر : سمنار- مراجعه

الفصل الدراسي الثاني

Normal histology

TITLE OF THE COURSE: Normal histology

Intedendterm : term (2)

Course duration : 15 weeks

Lectures : 2 hours per week

Credit hours : 3 hours

Week (1) Cell histology

Week (2) epithelial tissue

Week (3) Histology of connective tissue

Week (4) Connective tissue proper

Week (5) Cartilage

Week (6) bone

Week (7) Histology of the muscular system

Week (8) Histology of lymphatic & vascular system

Week (9)

Week (10) other tissues

اللغه العربيه -2

اسم المنهج : منهج اللغة العربية

الفترة الدراسية : الفترة الثانية

الفترة الزمنية للمنهج : 15 أسبوع

المحاضرات : ساعتان في الأسبوع ولمدة 15 أسبوع

عدد الساعات المعتمدة : 3 ساعات

الأهداف العامة للمنهج

عند إتمام دراسة المنهج ينبغي أن يكون الطالب قادراً علي :

1- معرفة أنواع وطرق النحت وقواعد التعريب والاختلافات بين اللغة العربية واللغة الإنجليزية فيالنبر

2- معرفة أسس التعريب والترجمة وما يتبع ذلك كتاريخ الترجمة وأهميتها وأنواعها وأساليبها .

3- معرفة إسهامات العلماء العرب في الحضارة والعلوم المختلفة

4- معرفة المستويات الصوتية وأنواعها ودلالاتها 

الأهداف الخاصة للمنهج

عند إتمام دراسة المنهج ينبغي أن يكون الطالب قادراً علي :

1- فهم طرق النحت ، وأهمية الترجمة وتاريخها ووحداتها وأنواعها ومستوياتها وجذورها عند العرب

2- معرفة قواعد الألفاظ والتعريب وإسهامات العلماء العرب في الحضارة والعلوم

3- معرفة أنواع المستويات اللغوية كالمستوي الصوتي والنحوي والدلالي .

4- معرفة الاختلافات بين اللغتين العربية والإنجليزية في النبر .

محتويات المنهج

الأسبوع الأول : أنواع وطرق النحت 

الأسبوع الثاني : الترجمة : تعريف وتاريخ الترجمة 

الأسبوع الثالث : الترجمة : أهمية الترجمة 

الأسبوع الرابع : الترجمة : الترجمة عند العرب

الأسبوع الخامس : الترجمة : وحدة الترجمة

الأسبوع السادس : الترجمة : الترجمة علي مستوي الفونيم والمورفيم

الأسبوع السابع : الترجمة : الترجمة علي مستوي الكلمة والجملة 

الأسبوع الثامن : الترجمة : الترجمة علي مستوي العبارة والنص

الأسبوع التاسع : التعريب : قواعد تعريب الألفاظ

الأسبوع العاشر : إسهامات علماء العرب في الحضارة العربية

الأسبوع الحادي عشر : نبوغ العرب في العلوم المختلفة

الأسبوع الثاني عشر : المستويات اللغوية : المستوي الصوتي 

الأسبوع الثالث عشر : المستويات اللغوية : المستوي النحوي

الأسبوع الرابع عشر : المستويات اللغوية : المستوي الدلالي 

الأسبوع الخامس عشر : بعض الاختلافات بين الإنجليزية والعربية في النبر 

Physiology -2

Course title: Physiology

Intended term: (2)

Course duration: 30 weeks

Lectures: 2 hours per week (60 hours)

Credit hour: 2 hours

Rationale:

This course is intended for medical laboratory science students.

Course description:

This course provides a basic background to the principal physiological systems of the human body, includes the blood autonomic nervous, cardiovascular, respiratory, gastrointestinal, endocrine, renal and central nervous system.

General Objectives:

By the end of this course, medical laboratory science students should:

1- State the role of the different body systems in regulating the internal environment.

2- Integrate information about various body systems and describe how one system impacts the other systems.

3- Given a description of an abnormality in a body system , students should be able to predict how this will affect homeostasis and how the body will attempt to compensate for the abnormality .

Specific Objectives:

 At the end of this course, the students should be able to:

1- Know the physiology of body fluids and their measurement.

2- Know the physiology of the blood, know the functions and physical characteristics of blood and know the physiology of the red cells, white cells & platelets.

3- Know the physiological basis of cardiac muscle, the vascular system, breathing gas exchange, lung volume, and lung capacity.

4- Know the composition and function of GIT hormones, gastric movement saliva, gastric juice, pancreatic secretion and bile.

5- Understand the types, structures, function and control of neuro-hormones, growth hormone, posterior pituitary hormones, thyroid hormones, and pancreatic hormones.

6- Understand the physiology renal clearance, renal circulation, counter-current mechanism, acid-base balance, and maturation disturbances.

7- Know the physiology of the sensory system reflexes, and motor mechanisms.

Instructional methods

Evaluation

Evaluation consists of:

Resources:

Lecture room, computer and multimedia projector

Course Content :

Week’s        lectures

Second semester

1- Respiratory System

2- Respiratory System

3- Respiratory System

4- Gastrointestinal Physiology

5- Gastrointestinal Physiology

6- Gastrointestinal Physiology

7- Endocrine System

8- Thyroid & parathyroid glands

9- The adrenal gland

10- Endocrine pancreas – Gonads

11- Renal System

12- Tubular reabsorption & tubular secretion – Micturition

13- The Central Nervous System

14- The Central Nervous System

15- The Central Nervous System

Instrumentation

Course title: Instrumentation

Intended term: (2)

Course duration: 15 weeks

Lectures: 2 hours per week (30 hours)

Credit hour: 3 hours

Rationale:

This course is intended for medical laboratory science students.

Course description:

This course provides a basic background to the principal of instruments that used in the laboratory

General Objectives:

By the end of this course, medical laboratory science students should:

1- State the role of the different of instruments that used in the laboratory

2- Integrate information about various Machines and equipments and describe how it works.

3- Given a description of an abnormality and the mistakes could be happened

Specific Objectives:

 At the end of this course, the students should be able to:

1- Know the main instruments used in the lab.

2- Know the usage of microscope, maintenance, cleaning & storage

3- Know the basis and principles of instrumentsused in the lab.

4- Know the composition and function of instruments used in the lab and their mechanisms.

Instructional methods

Evaluation

Evaluation consists of:

Resources:

Lecture room, computer and multimedia projector

Course Content :

Lectures

Week (1)

Microscopy- historical background.

Week (2)

 Light microscope –parts- types – principle.

Week (3)

 Other types of microscopes- dark field- phase contrast- fluorescence- electron microscopes.

Week (4)

 Balances.

Week (5)

 Centrifuge – types and uses.

Week (6)

Waterpathes

Week (7)

Sterilization & disinfection equipments- Oven- autoclaves

Week (8)

Nature of light-absorbance & transmission- Beer’s Low

Week (9)

 Colorimeter- spectrophotometer-

Week (10)

Automation- benefit of automation

Week (11)

 Tutorial.

Week (12)

Tutorial

Week (13)

Rivesion

Week (14)

Test

الثقافة الإسلامية -2

اسم المنهج : الثقافة الإسلامية

الفترة الدراسية : الفترة الأول

الفترة الزمنية للمنهج : 15 أسبوع

المحاضرات : ساعتان في الأسبوع ولمدة 15 أسبوع

عدد الساعات المعتمدة : 3 ساعات

الأهداف العامة للمنهج

عند إتمام دراسة المنهج ينبغي أن يكون الطالب قادراً علي :

محتويات المنهج

المحاضرات

الأسبوع الأول:  الأمراض الجنسية: ضريبة الإباحية.

الأسبوع الثاني:  الإسلام والإجهاض.

الأسبوع الثالث: الإسلام والخمر.

الأسبوع الخامس: الإسلام والتدخين.

الأسبوع السادس:  الإسلام وعلاج الرجل للمرأة.

الأسبوع السابع: الإسلام والزنا.

الأسبوع الثامن: الإسلام والإنعاش الصناعي.

الأسبوع التاسع: الإسلام والحيض.

الأسبوع العاشر: الإسلام والاستنساخ (1) – (2).

الأسبوع الحادي: الإسلام والتلقيح الصناعي.

الأسبوع الثاني عشر: الإسلام والموانع.

الأسبوع الثالث عشر: الإسلام والإيدز.

الأسبوع الرابع عشر: أعمال السنة

English language -2

Title of the course: English (2)

Intended term : term (2)

Course duration : 15 weeks

Lectures : 2 hours per week

Duration : 15 weeks

Credit hours : 3 hours per week

Rationale

This course is intended for medical laboratory science students

General Objective

By the end of this course , medical laboratory students should be able to :

Know the bases of English language grammar

Know how to write and speak English fluently

Specific Objective

Know the of nouns , verbs and adjective and their combination on between these items and syntax used in scientific writings .

Understand the infinitive , passive and omission uses and their combination with scientific syntax .

Know the use of miscellaneous syntax scientific writings .

Instructional methods

Lectures

Tutorials

Seminars

Evaluation

Final examinations run by internal examiners

Evaluation consists of:

M.C.Q. S:10%

Long essays : 40%

Short questions: 40%

Oral: 10%

Course contents

The course covers the following subjects:

Lectures

Week (1) Nouns 1Compound nouns Nouns with the same form as verbs Nouns + of this king Nouns + ending in-ion , y , ance,-ence ,-ment Nouns ending in – al , -or , -ability

Week (2)

nouns 2 Present , past participle + noun That , those to replace nouns Of + (adjective) noun That to replace singular noun Those to replace plural nouns

Week (3)

 Infinitive Was seen + Infinitive   Is said + Infinitive Can be + part participle + Infinitive , present participle Infinitive to replace so that , result that

Week (4)

Verbs Verbs formed with –fy ,en- , en Verb meaning show Verbs formed from nouns Has to replace other verbs

On … ing to replace when + verb

Week (5)

past participle Before being + past participle In , un before adjectives / past participle Is said to have + past participle When / if past participle

Week (6)

 Past and present participle Which + passive + to be + past participle Which + passive + to have + past participle Present participle to replace which + verb Contraction of which + present

Description of experiment (passive)

Week (7)

passivePassive with agent Passive without agent Contraction of which + passive Negative passive + infinitive Passive + to have + past participle Passive summery writing

Week (8)

adjectives Adjective ending in –ar , -ic Adjective + enough + infinitive Is said to be + adjective Un- , in- , im- , ab- + adjective

Week (9)

OmissionOmission to avoid repetition Omission of preposition Omitting nous to avoid repetition Do , does , did to avoid repetition

Week (10)

Miscellaneous -1

Known as On / after … ing For … ing purpose Question word + ever

Week (11)

 Miscellaneous-2 Provided with Able , unable to = can , cannot The case In that case By that meant

Week (12)

 Miscellaneous-3 Being showing result / reason Owing to the fact that Andvive versa And vice versa Not ………… but ………… The former / the later

Week (13)

 Miscellaneous-4

Of which to replace whose Having to replace which has , have

The more …………….. the more …………….By this is meant Although

Week (14)

 Miscellaneous-5

Differ / worry the reason for ………… is that Due to the fact that If it was not for

Week (15)

 Miscellaneous-6 Contraction of relative clause Phrase or clause to begin a sentence Possess to replace have Might to express doubt, possibility

Summary writing

Biology

Course title: Biology

Intended term: (2)

Course duration: 15 weeks

Lectures: 2 hours per week (30 hours)

Credit hour: 2 hours

Rationale:

This course is intended for medical laboratory science students.

Course description:

To develop an understanding of biological facts, principles and concepts.

 To promote an appreciation of the importance of observation and experimental work in the study of biology.

General Objectives:

By the end of this course, medical laboratory science students should:

1- State the role of the different of instruments that used in the laboratory

2- Integrate information about various Machines and equipments and describe how it works.

3- Given a description of an abnormality and the mistakes could be happened

Specific Objectives:

  1. Identify the relationship between biology and medical sciences.
    1. Differentiate between inductive and deductive methods as well as knowing the basic steps in the scientific method.
    1. Define the cell theory; identify the structure and function of the prokaryotic and eukaryotic cells as well as understanding cell bioenergetics and divisions.
    1. Recognise the basic architectural plan of the vertebrate body and its modifications in various classes and relate structure to function.
    1. Identify and recognise the role of insects and arthropods of medical importance and their control.
    1. Use the microscope and realise its importance as a biological tool.
    1. Dissect representative examples of some animal groups.
    1. Register the results of his laboratory investigations through scientific drawing, writing observations, constructing tables and plotting graphs.

Instructional methods

Evaluation

Evaluation consists of:

Resources:

Lecture room, computer and multimedia projector

Course Content :

Lectures

Week (1)

Introduction to cell biology.

Week (2)

Cell structure and function: definition of cell biology as theme in biology, methods of studying cells.

Week (3)

 Pro- and eukaryotic cells, animal, plant cells and fungal cells, modifications of cell surface.

Week (4)

Gross functions of cell components.

Week (5)

Cell membrane: molecular structure (fluid mosaic model), transport across membranes.

Week (6)

Cell cycle and cell divisions

Week (7)

The cell cycle (G0, G1, S, G, M), phases and significance of

Week (8)

Mitosis

Week (9)

Meiosis

Week (10)

 Morphology of chromosomes and karyotypes

Week (11)

Biological molecules

Week (12)

Enzymes

Week (13)

Tutorial

Week (14)

Revision

Week (15)

Test

Biochemistry

Course title: Biochemistry

Intended term: (2)

Course duration: 15 weeks

Lectures: 2 hours 

Credit hour: 2 hours

Week (1)

cell and Biomolecules:

Week (2)

Carbohydrates:

Week (3)

Week (4)

Lipids:

Week (5)

Week (6)

Protein Structure and Function:

Week (7)

Proteins:

Week (8)

Nucleic acids:

Week (9)

Vitamins:

Week (10)

Week (11)

Enzymes:

Week (12)

Week (13)

Hormones :

Week (14)

 Revision

Week (15)

Test

Lab safety

Course title: Lab safety

Intended term: (2)

Course duration: 15 weeks

Lectures: 2 hours per week (30 hours)

Credit hour: 2 hours

Rationale:

This course is intended for medical laboratory science students.

Week(1)

Orgnaization,administration&safety.

Week(2)

 Chemical hygiene, labeling, safety symbols.

Week(3)

 Biohazard, avoiding transmission of infectious disease.

Week(4)

 Decontaminations of surfaces &equipments.

Week(5)

 Safety manual, specimen handling, transporting and storage.

Week(6)

Handling, clearing of glass wares

Week(7)

 Electrical hazard, wounds, burn and corrosive materials

Week(8)

 First aid

Week(9)

 Storage of chemicals, glass wares, reagents and equipments

Week(10)

Laboratory design

Week(11)

 Tutorial.

Week (12)

 Laboratory administration, quality assessment, laboratory procedure manual

Week (13)

 Introduction to phlebotomy

Week (14)

 Introduction to quality assurance.

الفصل الدراسي الثالث

Microbiology-1

Intended term : term 3

Course duration : 15 weeks

Lectures : 2 hrs /

Practical : 3 hrs / week duration 15 weeks

Rational

This course is intended for medical laboratory science students

General Objectives

By the end of this course , the students is able to :

1- know the procedures adopted to identify and classify bacterial pathogens

2- Understand the basis of action of antimicrobial drugs , the pattern of bacterial resistance , and the methods of antimicrobial .

3- know the laboratory methods used for the isolation , identification , and serological diagnosis of bacterial diseases .

Specific Objectives

By the end of this course , the student should be able to :

1- Know the methods followed in culture of clinical specimens .

2- Know how to prepare culture media , how to store , and how to inoculate them .

3- Know the principles , procedures and reagents selected for the application of biochemical reaction used in the identification of pathogenic isolates .

4- Understand the modes of action of antimicrobial drugs and the procedures of sensitivity testing .

Instructional methods

Evaluation

Final examination runs by internal examiners

Evaluation consist of

Week (1)

Week (2)

Week (3)

Week (4)

 Preparation of culture media type of culture media ,

Week (5)

Week (6)

Week (7)

Week (8)

Week (9)

Week (10)

Week (11)

         Antimicrobial drugs and methods of action of antibiotic

 Week (12)

Week (13)

         Classification of g+ve bacteria and introduction of staphylococcus spp

Week (14)

Week (15)

class test

Practiacal

Week (1)

Lab safety in microbiology lab 

Week (2)

          Instrumentation and equipment use in bacteriology lab  

Week (3)

          Sterilization and disinfection inbacteriology lab  

Week (4)

          Preparation of culture media 

Week (5)

          Method of pouring of culture media and type of culture media

Week (6)

          Staining method mainly gram stain

Week (7)

          capsule stain and spore stain    

Week (8)

       Z. n stain       

Week (10)    Biochemical test for g+ve bacteria

          Catalase test 

Week (11)

Coaggulase test  

Week (12)

          Biochemical test   Monnitol salt agar and DNAas agar

Week (13)

            Isolation and identification of staph spp

Week (14)

             Revision 

Week (15)

          Class test

Clinical Chemistry -1

Course Title:  Introduction to Clinical Chemistry

Course Smester:3

Credit hours: 3

Course duration: (15 weeks)

Course description:

Clinical chemistry terminology, laboratory safety, units, solution, anticoagulants used in clinical chemistry, types, collection, storage, and changes of specimen, chemical analysis, colorimetery, urinary system and urine formation, chemical and physical examination of urine, glucosuria and reducing substances in urine and urine deposits and introduction to quality control.

Course objectives:

At the end of this course, the students should be able to:

  1. Define the following terms: units, colorimeter, and anticoagulant.
  2. Convert results from one unit format to another.
  3. Discuss colorimetry
  4. Be aware with collection and storage of specimen
  5. Be aware with laboratory safety
  6. Discuss urinary system function, disorders and laboratory findings.
  7. Define quality control.

Course contents (topics):

Theory:

  1. Introduction to clinical chemistry, Definitions and terminology, Role in medicine
  2. Safety in clinical chemistry, precautions and biohazards
  3. Units of measurements, conventional and SI
  4. Uses of glassware
  5. Methods of concentration expression: molarity, normality, percentage.
  6. Preparation of solutions:  from solids and dilution
  7. Collection, storage and transport of specimens, phlebotomy
  8. Anticoagulants used in clinical chemistry: types, function, mode of action and uses
  9. Buffers& PH: definition, PH measurement
  10. Operation and calibration of colorimeter and spectrophotometer, selection of wavelength
  11. Urine analysis – 1: urinary system and urine formation, physical & chemical examinations
  12. Urine analysis – 2: Deposit & microscopic examination
  13. Urine analysis – 3: Significance& Diagnostic values
  14. Reducing substances and ketone bodies: Synthesis & Significance 

Practical:

  1. Uses of glassware
  2. Safety in clinical chemistry, precautions and biohazards
  3. Preparation of solutions:  from solids and dilution
  4. Collection, storage and transport of specimens, phlebotomy
  5. Anticoagulants used in clinical chemistry: types, function, mode of action and uses
  6. Buffers& PH: definition, PH measurement
  7. Operation and calibration of colorimeter and spectrophotometer, selection of wavelength
  8. Urine analysis – 1: Physical examinations
  9. Urine analysis – 1: Physical examinations
  10. Urine analysis – 2: Chemical examinations
  11. Urine analysis – 2: Chemical examinations
  12. Urine analysis – 3: Deposit & microscopic examination
  13. Reducing substances and ketone bodies


Hematology -1

Course title: Basic hematology 1

Intended term : (3)

Course duration : 15 weeks

Study hours per week

Lecture : 2 hours

Practical : 3 hours

Credit hours : 3 hours

Rational

This course is intended for medical laboratory science students

General Objectives

By the end of this course , the medical laboratory students should be oriented in the hematology laboratory , and able to understand physiological principles of the production , constituents morphology and function of blood . Moreover , he should also be able to perform the basic hematological techniques as a first step in the diagnosis of blood diseases .

Specific Objectives

Upon the completion of the course the students should be able to :

Instructional methods

Evaluations

Final examinations run by internal examiners

Evaluation consist of :

Course description

Lectures

Week (1)

Introduction to hematology

Week (2)

Blood collection , storage and transport

Week (3)

Origin development of hemopoietic tissues

Week (4)

Red blood cell production : “Erythropoiesis”

Week (5)

Basic hematological techniques :Hemocytometry

Significance and source of errors

Week (6)

Platelet production “Thrombopoiesis”

Definition and promotion

Regulation and substances needed

Week (7)

Red blood cell count

Week (8) 

Hemoglobin  Synthesis

Types and structures

Week (9)

Break down

Week (10)

Week (11)

 ESR

Week (12)

 White cell production “Leucopoiesis”

Definition and promotion Regulation and substances needed

Week (13)

 Principle and procedures Count and interpretation of results

 Platelet normal morphology and function

Week (14)

Blood film examination Macroscopic examination

Week (15)

White blood cell count

Practical

Week (1)

 Introduction “Laboratory safety , precautions and restrictions”

Week (2)

 Hematology laboratory environment , equipment , apparatuses and basic operations

Week (3)

 Preparation of solutions and stains and units of measurement

Week (4)

 Differentiation of hemopoieticcells : Red blood cell normal morphology

Week (5)

 Blood sample collection and anticoagulants

Week (6)

Haemocytometry

Week (7)

Red blood cell count 1

Week (8)

 Red blood cell count 2

Week (9)

 Hemoglobin estimation “cyanomethaemoglobin method”

Week

 (10) Hemoglobin curve and chart

Week (11) Packed cell volume

Week (12) Calculation of absolute values

Week (13) Erythrocyte sedimentation rate

Week (14) White blood cell count

Parasitology -1

Course title: Medical Parasitology

Intended term : 3

Course duration : 15 weeks

Practical : 3 hrs per week

Credit hours : 3 hours

Objectives

By the end of this course medical laboratory student should be able to :

Intructional methods

Evaluation

Written and practical examinations held at the end of the two terms (4-5) by internal examiners .

Course content

Theoretical sessions

Week (1)

     Introduction of medical Parasitology

Week (2)

     Classification of parasite and possiple parasite in the sample 

Week (3)

              Intestinal protozoa entamobahistolytica

Week (4)

              giardia lamblia

Week (5)

     Balantidium coli

Week (6)

              Intestinal coccidian species      

Week (7)

     Classification of plasmodium

P.falacipram

Week (9)

     P. vivax

Week (10)

     p.malarea and P. ovale

Week (11)

     Complication and lab diagnosis of malaria

Week (12)

     Sarcocystis ,Penumocysis (lecture)

Week (13)

     Presentation 

Week (14)

reviw)

Week (15)

     Class test

Practical

Week (1)Lab safty and how to use microscope

Week (2)Normal structure  of stool and wet preparation

Week (3)Concentration techniques

Week (4) Lab diagnosis of E. histolytica

Week (5) Lab diagnosis of giardia lamblia

Week (6)Lab diagnosis of B. coli

Week (7)Lab diagnosis of intestinal coocidia

Week (8)Colletion of blood and type of stain

Week (9)How to make blood film and preparation of giemsa stain

Week (10)Lab diagnosis of malaria parasite

Week (11)Lab diagnosis of malaria parasite

Week (12) Lab diagnosis of malaria parasite

Week (13)Presentation

Week (14)Revision

Week (15)Lab examination

Histopathology -1

Title of the course:        basic histo- technology

Intended term:     three

Course duration: 15 weeks.

Study hours per week: (2 theory+2practical).

Credit hours:3

Pre-requisite course: Histology and anatomy

Course description:

This course will enable the student to perform the common techniques in tissue processing and produce stained sections by using the correct instruments. Instructions on the maintenance of such instrument will be given.

Specific objectives:

Upon completion of this course the student should be able to:

  1. Understand definition, sources and types of histological specimens.
  2. Understand and identify  methods used in preparation of tissue and cells

3- Explain fixatives and their action in tissue.

4- Understand and identify the decalcification and methods used for decalcification.

5-Understand and identify the processing steps.

6- Understand and identify types of embedding media

7- Understand and identify the frozen section techniques and theirs application.

8- Understand and identify Microtomy and microtomes

9- Understand and identify the material and instrument used in paraffin cut.

10- Understand the adhesives media and their uses

11- Understand and identify the theory of staining and types of staining reaction.

12- Understand and identify the general staining procedure using Hematoxylin and eosin stain.

13- Discuss the mounting media and their uses in preserving stained sections and their types

1-Lectures:

WeeksLectures
1Introduction to histopathology   and Work flow in histopathology and cytology lab
2Aim of histopathology and cytology study, methods of tissue and cells preparation (dissociation, smear preparation, sectioning, vital staining and impression method)
3Fixation and fixatives  , principles , theoretical aspects , aims and classifications
4Factors involved in fixation, ideal fixatives, bad fixation and fixation of special substances or organs , secondary fixation and preservation of specimens
5Decalcification of bone  ,checking the completion of decalcification and treatment following decalcification
6Principles of tissue processing, steps, and factors influencing the rate of tissue processing.
7Embedding media, vacuum impregnation and orientation of tissues.
8 frozen techniques (applications, cryostat, freezing microtome, freeze drying and freeze     substitution)
9 Automatic and manual tissue processing.
10Types of microtomes ,  types of knives  and remedies
11General theory of stain and Methods of coloration
12 Basis of staining and factors contributing to tissue dye affinity
13Introduction to Hematoxylin
14Alum Hematoxylin and Eosin
15Hematoxylin and eosin (iron Hematoxylin) , other Hematoxylin and quality control
16Resinous mounting media and other mounting media.

2-Practical :

PracticalWeeks
Introduction to histopathology and cytology practice (Instrumentation)1
 The work flow in histopathology and cytology lab2
Methods of preparation and sample reception and selection3
Preparation of routine fixatives (10% formalin , 10% formal saline ,  Carnoy,s and Bouin,s fixatives4
Preparation of decalcifying solution, decalcification 5
Tests for end point of decalcification6
Rapid tissue processing7
Routine tissue processing steps up to impregnation manual and automated8
Embedding in paraffin wax, blocking9
Handle with microtome, Cutting by rotary microtome steps up to prepare paraffin cut section10
Staining with Mayer’s Hematoxylin (progressive)11
Staining with Harri`s Hematoxylin (regressive)12
Staining with Harri`s Hematoxylin (progressive)13
Staining with Cole’s Hematoxylin14
Staining with Weigert`s Hematoxylin15

Basic Immunology

Intended term: term 3

Course duration: 15 weeks

Lectures : 2 hrs / duration 15 week s

Credit hours: 2

Rational

This course is intended for medical laboratory science students

Instructional methods

Evaluation

Final examination runs by internal examiners

Evaluation consist of

Lectures

Week (1)Introduction to immunology.

Week (2)

Tissue and cell of immune system

Week (3)

Innate and adaptive immunity

Week (4)

Primary and secondary immune response

Week (5)

B & T cell interaction

Week (6)

Immunoglobulin

Week (7)

Antigen presentation

Week (8)

Major histocompatibility complex

Week (9)

T cell 

Week (10)

Complement

Week (11)

Immunological tests & immune-based investigations

Sensitivity testing

Week (12)

       Tutorial

Week (13)

Test

Community Health

Intended term: term 3

Course duration: 14 weeks

Lectures : 2 hrs / duration 15 week s

Credit hours: 2

Rational

This course is intended for medical laboratory science students

Instructional methods

Evaluation

Final examination runs by internal examiners

Evaluation consist of

Lectures

Week (1)

Introduction to community medicine.

Week (2)

Health dimension

Week (3)

Health determinants

Week (4)

Dynamic of infectious diseases

Week (5)

Agent

Week (6)

Mode of transmission

Week (7)

Host

Week (8)

Diseases control

Week (9)

Diseases prevention

Week (10)

Tutorial

Week (11)

Tutorial

Week (12)

      Test

الفصل الدراسي الرابع

Microbiology -2

Intended term : term 4

Course duration : 15 weeks

Lectures : 2 hrs / duration 15 week s

Practical : 3 hrs / week duration 15 weeks

Credit hours: 3

Rational

This course is intended for medical laboratory science students

General Objectives

By the end of this course , the students is able to :

1- know the procedures adopted to identify and classify bacterial pathogens

2- Understand the basis of action of antimicrobial drugs , the pattern of bacterial resistance , and the methods of antimicrobial .

3- know the laboratory methods used for the isolation , identification , and serological diagnosis of bacterial diseases .

Specific Objectives

By the end of this course , the student should be able to :

1- Know the methods followed in culture of clinical specimens .

2- Know how to prepare culture media , how to store , and how to inoculate them .

3- Know the principles , procedures and reagents selected for the application of biochemical reaction used in the identification of pathogenic isolates .

4- Understand the modes of action of antimicrobial drugs and the procedures of sensitivity testing .

Instructional methods

Evaluation

Final examination runs by internal examiners

Evaluation consist of

Week (1)  gram positive cocci

streptococcusspp

Week (2) streptococcusspp

week(3) gram negative cocci

Week (4) Neisseria gonorrhaeae

Week (5) gram positive bacilli

Week (6) Bacillus spp (anthracis ,cerus)

Week (7) Coryne bacterium dipheteriae

Week (8) Clostridium species

Week (9) Clostridium species

Week (10) Clostridium species

Week (11) Nocardia and

Week (12) actinomysisspp

Week (13) classification of enterobacteriacea and general characteristic of it

Week (14) Biochemical test for gram negative bacteria

Week (15) Test class

Practical

Week (1)        Lab diagnosis of stereptocoocuspyogens

Week(2)         Lab diagnosis of streptococcus agalacia

Week (3)        Lab diagnosis  ofstereptococcus pneumonia

Week (4)        Lab diagnosis of other speciese of stereptococcus

Week (5)        Lad diagnosis of bacillus spp

Week (6)        Lab diadnosis of corynbacterium

Week (7)        Biochemical test for gram negative bacteriaOxidase test

Week (8)        KIA test and indole test    

Week (9)        Citrate test and urease test

Week (10)      VP test methyl red test

Week (11)      Other biochemical test for gram negative bacteria

Week (12)      Revision

Week (13)      Presentation

Week (14)      Class test

Week (15 )     Final examination

Clinical chemistry -2

Course Title:  Renal system & Carbohydrates

Course Semester: 4

Credit hours: 3

Prerequisites:  Study the following curses:

  1. General and analytical chemistry
  2. Biochemistry
  3. Introduction to clinical chemistry
  4. Physiology

Course duration: (14-16 weeks)

Course description:

Kidney anatomy, kidney physiology, renal functions test, non protein nitrogenous substances (blood urea, creatine and creatinine, renal clearance, urates, kidney diseases, carbohydrate and blood glucose homeostasis, glucose tolerance, hyperglycaemia and hypoglycaemia, investigation and diagnosis of DM, diabetic ketoacidosis (DKA) and laboratory findings, glycogen storage disease.

Course objectives:

At the end of this course, the students should be able to:

  1. Discuss physiology of kidney, mechanisms of fluid maintenance& electrolytes balance.
  2. Define glomerular filtration rate (GFR) and clearance.
  3. Define non-proteinnitrogenous substance (NPN).
  4. Discussrenaldiseases
  5. discuss urate synthesis, metabolism&abnormalities
  6. discuss the CHO metabolismdisorders
  7.  discuss blood glucose and hormonal regulation
  8. define diabetes mellitus (DM), types, methods of investigation and complications

Course contents (topics):

Theory:

  1. Renalsystem:anatomy, physiology
  2. Renalfunction test.
  3. Renaldiseases:nephritic syndrome, renalfailure.
  4. Non proteinnitrogenoussubstances:bloodurea.
  5. Non proteinnitrogenoussubstances:Creatine&creatinine
  6. Non proteinnitrogenous substances : Urates
  7. Carbohydrates: metabolism and blood glucose homeostasis.
  8. Hyperglycemia&hypoglycemia
  9. Diabetesmellitus
  10.  Investigations and diagnoses of diabetes mellitus
  11. Glucose tolerance test
  12.  Complication of diabetes
  13. Glycogenstoragediseases.

Practical:

  1. Blood urea (Chemical)
  2. Blood urea (Enzymatic)
  3. Serum creatinine (Jaffe)
  4. Serum creatinine (Kinetic)
  5. Creatinine clearance
  6. Creatinine STD curve
  7. Serum uric acid (Chemical)
  8. Serum uric acid (Enzymatic)
  9. Blood glucose (Chemical)
  10. Blood glucose (Enzymatic)
  11.  GTT
  12.  HbA1c


Hematology -2

 Course title: Immunohematology

Intended term : (6)

Course duration : (15) weeks

Study hours per week :

Credit hours : 3 hours per week

Rationale

This course is intended for medical laboratory science students

General Objectives

By the end of this course , medical laboratory students should be able to understand applications of blood components organization , planning , and management of blood bank plus laboratory diagnosis of blood transfusion complication . Moreover , he should also understand pathophysiology , and laboratory diagnosis of HDN & HTR .

Specific Objectives

Upon the completion of the course the students should be able to :

Instructional methods

Evaluation

Final examinations run by internal examiners

Evaluation consist of :

Course description

The course covers the following subjects

Lectures

Week (1) introduction to immunohaematology

Week (2) antigens

Week (3) antibodies

Week (4) Ag /Ab reaction  

Week (5) complement

Week (6) ABO blood group

Week (7) ABO blood groupsystem

Week (8) tutorial

Week (9) rhesus system

Week (10) rhesus system

Week (11) minorbloodgruop

Red blood cell membrane

Week (12) class test   

Week (13) quality control

Practical

Week (1)     test

Week (2)     Platelets normal and abnormal morphologies

Week (3)     Platelet count 1

Week (4)     Platelet count 2

Week (5)     Preparation of stains and Buffers

Week (6)     Blood film preparation “spreading”

Week (7)     Blood film spreading , fixation and staining

Week (8)     Blood film spreading , fixation and staining

Week (9)     Blood film examination

Week (10)   Differential leucocyte count

Week (11)   Abnormal morphology of red cells

Week (12)   Abnormal morphology of blood cells

Week (13)   Completehaemogram “normal sample”

Week (14)   Completehaemogram “normal sample”

Week (15)   Completehaemogram “abnormal sample”

Histopathology -2

Title of the course: Special histo- technologies

Intended term:     four

Course duration: 16 weeks.

Study hours per week: (2theory +2 practical).

Credit hours:3

Pre-requisite course: Student should know and study Specific objects and practical course of term three and four.

Course description:

          By the end of this course medical laboratory student should be oriented in Special staining technique for Protein and nucleic acid, Carbohydrate, pigment, lipids, Connective tissue and microorganism elements either advance or histochemical.

Specific objectives:

Upon the completion of this course the student should be able to:

1. Differentiate between general and special staining technique.

2. Understand and identify the Proteins their structure, function and their diagnostic applications and methods of demonstration.

3. Understand and identify the Nucleic acids, their structure, function and their diagnostic applications and methods of their demonstration.

4. Understand and identify the carbohydrates, their classification and their diagnostic applications and methods for demonstration of glycogen.

5. Understand and identify the mucin, classification, diagnostic applications and methods of demonstration.

6. Understand and identify the amyloid, pathogenicity, classification, diagnostic applications and methods of demonstration.

7.  Understand and identify the Connective tissue element, diagnostic applications and methods of demonstration.

8. Understand and identify the Lipids, classification and diagnostic applications and methods of demonstration.

9. Understand and identify the Pigments, classification, diagnostic application and methods of demonstration.

10. Understand and identify different microorganisms that infect tissues and methods of demonstration.

1-lectures

LecturesWeeks
Differences between general and special staining techniques1
Proteins ( classification  and methods of demonstration: histochemical and advance methods)2
Nucleic acids( structure and its diagnostic medical importance)3
Nucleic acids( methods of demonstration : histochemical and advance methods)4
Carbohydrates (classification , glycogen normal location, pathological conditions and fixation, methods of demonstration )5
Carbohydrates: mucins (types, normal location , pathological applications and methods of demonstration )6
Other carbohydrates: starch, cellulose and chitin7
Connective tissues: (components: cells and intercellular substances; its types: adipose, areolar, dense and cartilages)8
Connective tissues (collagen and elastic fibers and reticular fiber) ,demonstration and diagnostic applications9
Pigments: endogenous and mineral (definition , classification and its diagnostic medical importance)10
Pigments artifact and exogenous :  demonstration and diagnostic medical importance11
Lipids (classification, pathological conditions, and its diagnostic medical importance and methods of demonstration )12
Amyloid (definition, Pathogenesis,  composition and classification)13
Demonstration of amyloid (Congo red techniques, metachromatic method and fluorescent and others  methods)14
Microorganism :bacteria , virus  and fungi15
Microorganism :staining technique (bacteria,  mycobacterium, fungi)16


2-Practical :

PracticalWeeks
Fulgent reaction and Methyl Green Pyronin stain1
Periodic Schiff’s reaction (PAS) and PAS with diastase2
Alcian blue for acid mucin3
PAS technique for neutral mucin4
Combined Alcian blue and PAS for acid and neutral mucin5
van Gienson technique for collagen fiber6
Masson trichrome for collagen fiber7
Verhoff`s  Hematoxylin for elastic fiber8
Gordon and Sweet’s for reticulin fiber 9
Perl’s Prussian blue for Hemosiderin pigment10
Schmorl’s reaction for Melanin pigment and Masson-Fontana for Melanin pigment11
Sudan black methods for lipids12
High man’s Congo red for amyloid13
Microorganism staining method : Giemsa and gram stain14
Microorganism staining method ,:ZN stain15
Microorganism staining method :  silver method for fungi16

Parasitology -2

Intended term : 4

Course duration : 15 weeks

Credit hours : 2

Practical: 3hrs

Rational

This course is intended for medical laboratory science students

General Objectives

By the end of this course medical laboratory students should be able to :

Specific Objectives

By the end of this course , candidates should be able to :

Instructional methods

Evaluation

Written and practical examinations held at the end of the two terms (3-4) by internal examiners .

Written exam : 40%

Practical exam: 50%

Assignments, log books, attendance, etc … 10%

Course content

Theory

Lecture

Week (1)       Blood and tissues protozoa classification 

Week (2)       Trypanosome I (African trypanosomiasis)

Week (3)       Trypanosome II (American Trypanosomiasis)

Week (4)        Lieshmania parasite classification 

Week (5)       Leishmania II (Visceral Leishmaniasis )

Week (6)       Leishmania I (coetaneous Leishmaniasis and mucocoeteous

Week (7)       Trichomonas vaginalis

Week (8)       Toxoplasma gondii

Week (9)       Babasiaspp

Week (10)      Introduction for helminthes

Week (11)      Presentation

Week (12)      Revision

Week (13)      Presentation

Week (14)      Presentation )

Week (15)      Class test

Practical

Week (1)       Type of stain for blood specimen

Week (2)       Lab diagnosis of African trypanosomasis

Week (3)        Lab diagnosis of American trypanosomasis

Week (4)       Lab diagnosis of visceral leishmanasis

Week (5)       Lab diagnosis of cutanoeus and mucocutianousleishmanasis

Week (6)       Lab diagnosis of trichmonas vaginalis

Week (7)       Lab diagnosis of toxoplasma gondii

Week (8)        Lab diagnosis of babesiaspp

Week (9)        Intestinal parasites (Seminar)

Week (10)      Leishmania I (coetaneous Leishmaniasis) – seminar

Week (11)      Leishmania II (Visceral Leishmaniasis ) – seminar

Week (12)      reviw

Week (13)      Presentation

Week (14)       Plasmodium sppreviw

Week (15)       Class test

 General Pathology

Course title : General Pathology

Intended  term: (4)

Course duration : 14 weeks

Credit hours: 2 hours

Rationale

This course is intended for medical laboratory science students

General Objectives

By the end of this course medical laboratory students should understand pathological terminology, nomenclature, and laboratory investigations intended to diagnose these types of tumor.

Lectures

Week (1)               Cell Injury degenerating necrosis

Week (2)               Inflammation

Week (3)               Acute inflammation

Week (4)               Chronic inflammation

Week (5)               Tissue Repair

Week (6)               Neoplasia

Week (7)               Types of tumors

Week (8)               Benign tumors

Week (9)               Malignant tumors

Week (10)             Pathology of female reproductive tract

Week (11)             Pathology of male reproductive tract

Week (12)             Pathology of body fluids

Week (13)             Tutorial

Week (14)             Rivision

Epidemiology

Course title: Epidemiology

Intended term: term 4

Course duration: 14 weeks

Lectures : 2 hrs / duration 15 week s

Credit hours: 2 hours

Rational

This course is intended for medical laboratory science students

Instructional methods

Evaluation

Final examination runs by internal examiners

Evaluation consist of

Lectures

Week (1) Introduction .

Week (2) Morbidity calculation

Week (3) Mortality calculation

Week (4) Survey

Week (5) Study design

Week (6) Cross-section

Week (7) Case-control

Week (8) Cohort

Week (9) Experimental

Week (10) Outbreak investigation

Week (11) Surveillance

Week (12)  Tutorial

Week (13)   Test

الفصل الدراسي الخامس

Microbiology -3

Intended term : term 5

Course duration : 15 weeks

Lectures : 2 hrs / duration 15 week s

Practical : 3 hrs / week duration 15 weeks

Credit hours: 3

Rational

This course is intended for medical laboratory science students

General Objectives

By the end of this course , the students is able to :

1- know the procedures adopted to identify and classify bacterial pathogens .

2- Understand the basis of action of antimicrobial drugs , the pattern of bacterial resistance , and the methods of antimicrobial .

3- know the laboratory methods used for the isolation , identification , and serological diagnosis of bacterial diseases .

Specific Objectives

By the end of this course , the student should be able to :

1- Know the methods followed in culture of clinical specimens .

2- Know how to prepare culture media , how to store , and how to inoculate them .

3- Know the principles , procedures and reagents selected for the application of biochemical reaction used in the identification of pathogenic isolates .

4- Understand the modes of action of antimicrobial drugs and the procedures of sensitivity testing .

Instructional methods

Evaluation

Final examination runs by internal examiners

Evaluation consist of

Week (1)

Ecoli

Week (2)

Klebsiellaspp

Week (3)

citrobacter ,enterobacter ,serraciaspp

Week (4)

shigellaspp

Week (5)

salmonellaspp

Week (6)

proteusspp

Week (7)

Week (8)

pseudomonasspp

Week (9)

Haemophllusspp

Week (10)

Bordetela and pasturllaspp

Week (11)

 Brucella spp

Week (12)

Mycobacterium tuberculosis and  Mucobacteriumlepry

Week (13)

Campylobacter and helicobacter

Week (14)

        Mycoplasma

Week (15)

Spirochetsspp

Practical

Week (1)

Lab diagnosis of E. coli

Week (2)

Lab diagnosis of klebseilla pneumonia

Week (3)

Lab diagnosis of citrobacter

Week (4)

diagnosis of enterobacter

Week (5 )

Lab diagnosis of serraciaspp

Week (6)

Lab diagnosis of shigellaspp

Week(7)

Lab diagnosis if salmonella spp

Week(8)

Lab diagnosis of proteusspp

Week(9)

Lab diagnosis of pseodomanasspp

Week (10)

Lab diagnosis of vibrio cholera

Week(11)

Lab diagnosis of brucellaspp

Week (12)

Lab diagnosis of mycobacterium tuberculosis

Week (13)

Lab diagnosis of compylobacter and helicobacter

Week (14)

Revision

Week (15)

Class test

Clinical Chemistry -3

Course Title:  Iiver & plasma proteins

Course Semester: 5

Credit hours: 3

Prerequisites:  Study the following curses:

  1. General and analytical chemistry
  2. Biochemistry
  3. Introduction to clinical chemistry
  4. Physiology

Course duration: (14-16 week)

Course description:

Liver physiology, synthetic and storage function of liver, excretory and detoxifying function of liver, urine bile, urobilinogen and bile salts, investigation and laboratory findings of jaundice, hepatitis and cirrhosis, cholestasis and gall stone, plasma total proteins, bilirubin metabolism, calcium, phosphorus.

Course objectives:

 At the end of this course, the students should able to:

Course contents (topics):

Theory:

  1. Liver anatomy and physiology
  2. Liver function
  3. Classification of jaundice
  4. Liver diseases
  5. Assessment of liver function
  6. Enzyme test in liver disease
  7. Calcium
  8. Phosphorus
  9. Plasma proteins: classification&synthesis.
  10. Plasma proteins:metabolism&functions
  11. Plasma proteins: disorders& method of separation
  12. Plasma proteins:Albumin, globulins and fibrinogen
  13. Methods of protein estimation: chemical&refractometry

Practical:

  1. Total plasma protein (biuret commercial)
  2. Total plasma protein (biuret prepared)
  3. Protein STD curve
  4. Albumin (BCG)
  5. Albumin STD curve
  6. Globulin
  7. Serum bilirubin
  8. Liver enzymes (AST)
  9. Liver enzymes (ALT)
  10. Liver enzymes (ALP)
  11. Serum calcium
  12. Serum phosphorus


Clinical Immunology

Intended term: term 5

Course duration: 15 weeks

Lectures : 2 hrs / duration 15 week s

Credit hours: 2

Rational

This course is intended for medical laboratory science students

Instructional methods

Evaluation

Final examination runs by internal examiners

Evaluation consist of

Lectures

Week (1)Immunoregulation and Tolerance.

Week (2) Autoimmune disease & hypersensitivity

Week (3)  Hypersensitivity

Week (4) Autoimmune disease – SLE

Week (5) Diabetes mellitus

Week (6) Hashemotosthyroditis

Week (7) Mycenia gravis

Week (8) Immunity to infectious disease

Week (9) Immunity to tumors

Week (10)Transplantation

Week (11)Immunological tests & immune-based investigations

Week (12) Tutorial

Week (13) Test

Hematology -3

Course title : Red Blood Cell Disorders

Intended  term 5

Course duration : 15 weeks

Credit hours: 3 hours

Rationale

This course is intended for medical laboratory science students

General Objectives

By the end of this course medical laboratory students should Understand pathophysiology , mechanism , and laboratory investigations intended to diagnose these types of anemias .

Specific Objectives

Upon the completion of the course the student should be able to :

Instructional methods

Evaluations 

Final examinations by examiners , the evaluation consist of :

M.C.Q : 10%

Short constructive questions : 20%

Practical : 40%

Oral : 10%

Course description

The course covers the following subjects

Lectures

Week (1) RBCs membrane

Week (2) RBCs metabolism

Week (3)Abnormal RBCs morphology

Week (4) RBCs inclusion bodies

Week (5)Introduction to anemia

Week (6) Iron deficiency anemia

Week (7) Sidroblastic anemia

Week (8) Anemia of chronic disease & lead poisoning

Week (9) Introduction to hemolytic anemia

Week (10) Sickle cell anemia

Week (11) Thalassaemia

Week (12) Acquired hemolytic anemia

Week (13)A plastic anemia

Week (14) Hemolytic anemia due to external defect Autoimmune and drug induced hemolytic anemia

Week (15) Diagnosis of acquired hemolytic anemia Hematological findingsImmunoassay

Practical

Week (1) Completehemogram (normal samples)

Week (2) Completehemogram (iron deficient samples)

Week (3) Peripheral blood and bone marrow spots

Week (4) Assessment of serum iron and IBC

Week (5) Iron stain

Week (6) Completehaemogram (vitamin B12 & folic deficient samples)

Week (7) Peripheral blood and bone marrow spots

Week (8) Assessment of serum vit B12

Week (9) Assessment of serum folic acid

Week (10) Reticulocyte count

Week (11) Osmotic fragility test

Week (12) Osmotic fragility test (24hours incubation)

Week (13) G6PD screening test

Week (14) Pyrovate kinase assessment

Week (15) Direct anti globulin test

Molecular biology -1

Course title: Molecular biology 1

Intended term : 5

Course duration : 15 weeks

Credit hours : 2

Practical: 2hrs

Rational

This course is intended for medical laboratory science students

General Objectives

By the end of this course medical laboratory students should be able to :

Lecture

Week (1)           General introduction, definitions of terminology&   History  

Week (2)            DNA structure and function

Week (3)           RNA  structure and function

Week (4)            DNA Replication

Week (5)            RNA Transcription

Week (6)            post transcription 

Week (7)            genetic code and Translation

Week (8)            post translation and Restriction Enzymes

Week (9)            mutation

Week (10)       application of molecular biology Polymerase Chain Reaction (PCR)

Week (11)   gelelectrophorasis (requirement and preparation and function)

Week (12)         Regulation

Week (13)         Presentation

Week (14)          Revision

Week (15)          Class test

Histopathology -3

Title of the course:        Special histo- technologies

Intended term:     Five  

Course duration: 15 weeks.

Study hours per week: (2theory +2 practical).

Credit hours: 3

Pre-requisite course: Student should know and study Specific objects and practical course of term three and four.

Course description:

          By the end of this course medical laboratory student should be oriented in Special staining technique for Protein and nucleic acid, Carbohydrate, pigment, lipids, Connective tissue and microorganism elements either advance or histochemical.

Specific objectives:

Upon the completion of this course the student should be able to:

1. Differentiate between general and special staining technique.

2. Understand and identify the Proteins their structure, function and their diagnostic applications and methods of demonstration.

3. Understand and identify the Nucleic acids, their structure, function and their diagnostic applications and methods of their demonstration.

4. Understand and identify the carbohydrates, their classification and their diagnostic applications and methods for demonstration of glycogen.

5. Understand and identify the mucin, classification, diagnostic applications and methods of demonstration.

6. Understand and identify the amyloid, pathogenicity, classification, diagnostic applications and methods of demonstration.

7.  Understand and identify the Connective tissue element, diagnostic applications and methods of demonstration.

8. Understand and identify the Lipids, classification and diagnostic applications and methods of demonstration.

9. Understand and identify the Pigments, classification, diagnostic application and methods of demonstration.

10. Understand and identify different microorganisms that infect tissues and methods of demonstration.

1-lectures

LecturesWeeks
Differences between general and special staining techniques1
Proteins ( classification  and methods of demonstration: histochemical and advance methods)2
Nucleic acids( structure and its diagnostic medical importance)3
Nucleic acids( methods of demonstration : histochemical and advance methods)4
Carbohydrates (classification , glycogen normal location, pathological conditions and fixation, methods of demonstration )5
Carbohydrates: mucins (types, normal location , pathological applications and methods of demonstration )6
Other carbohydrates: starch, cellulose and chitin7
Connective tissues: (components: cells and intercellular substances; its types: adipose, areolar, dense and cartilages)8
Connective tissues (collagen and elastic fibers and reticular fiber) ,demonstration and diagnostic applications9
Pigments: endogenous and mineral (definition , classification and its diagnostic medical importance)10
Pigments artifact and exogenous :  demonstration and diagnostic medical importance11
Lipids (classification, pathological conditions, and its diagnostic medical importance and methods of demonstration )12
Amyloid (definition, Pathogenesis,  composition and classification)13
Demonstration of amyloid (Congo red techniques, metachromatic method and fluorescent and others  methods)14
Microorganism :bacteria , virus  and fungi15
Microorganism :staining technique (bacteria,  mycobacterium, fungi)16

2-Practical :

PracticalWeeks
Fulgent reaction and Methyl Green Pyronin stain1
Periodic Schiff’s reaction (PAS) and PAS with diastase2
Alcian blue for acid mucin3
PAS technique for neutral mucin4
Combined Alcian blue and PAS for acid and neutral mucin5
van Gienson technique for collagen fiber6
Masson trichrome for collagen fiber7
Verhoff`s  Hematoxylin for elastic fiber8
Gordon and Sweet’s for reticulin fiber 9
Perl’s Prussian blue for Hemosiderin pigment10
Schmorl’s reaction for Melanin pigment and Masson-Fontana for Melanin pigment11
Sudan black methods for lipids12
High man’s Congo red for amyloid13
Microorganism staining method : Giemsa and gram stain14
Microorganism staining method ,:ZN stain15
Microorganism staining method :  silver method for fungi16

Parasitology -3

course title :  Helminthology    

Intended term : (5)

Course duration : (15) weeks

Lectures : 2 hours per week

Practical : 3 hours per week

Credit hours : 3 hours

Rationale

This course is intended for medical laboratory science students

General Objectives

By the end of this course , medical laboratory students should be able to :

Understand the pathogenicty of parasites of medical importance

Understand the features and transmission methods of parasitic diseases

Know the technical procedures employed in the diagnosis of parasitic infections in the laboratory .

Specific Objectives

By the end of this course the students should be able to :

1.Understand the taxonomy and morphology of helminthes

2.Understand the factors affecting nutrition , growth and methods of reproduction and multiplication of platyheminthes of medical importance

3.Understand the pathogenicity and toxin production of platyheminthes of medical importance .

4.Understand the features and spread of platyeminthes .

5.Know the laboratory techniques use for platyheminthesdiagnosis .

Instructional methods

Lectures

Practical

Tutorials

Evaluation

Final examinations run by internal examiners

The evaluation consists of :

M.C.Q : 10%

Long essays : 20%

Short questions : 10%

Practical : 50%

Oral : 10%

Course Content

The course covers the following subjects

Lectures :

Week (1) Introduction to Heminthology (Classification)

Week (2) Cestod (Introduction and classification)

Week (3) Taeniasaginata

Week (4) Taeniasolium ,Hymenolipes nana , Hymenolipesdeminuta

Week (5) Echinococusgranulosus

Week (6) Diphylobothriumlatum and diphilidumcaninum

Week (7) Clasifiation of tematode and schistosomahaematobium

Week (8) Schistosoma japonicum& Schistosoma intercalatum

Week (9) Schistosoma mansoni

Week (10) Faciolahepatia and faciolagigentica

Week (11) faciolopsisbuski

Week (12) Paragonimus spp

Week (13) Clonochissinensisanddicrocelum dendiriticum

Week (14) Revision

Week (15) Class test

Practical

Including the principal laboratory techniques and diagnostic measures :

Week (1) Orientation to Helminthology diagnosis

Week (2) Lab diagnosis of tinea spp

Week (3) Lab diagnosis of H. nana and diminuta

Week (4) Lab diagnosis of diphylobothriumlatum and D. caninum

Week (5) Lab diagnosis ofSchistosoma haematobium ova and snail

Week (6) laboratory diagnosis of schistosomiasismansoni and japonicum

Week (7) Lab diagnosis ofFasciolahepatica , and Fasciola gigantic

Week (8) Lab diagnosis of Fsciolopsisbuski

Week (9) Lab diagnosis of Chlonorchessienensisall stages

Week (10) Lab diagnosis of Paragonimus westermani all stages

Week (11) Lab diagnosis of dicrocellum dendiriticum

Week (12) Presentation       

Week (13) Presentation

Week (14) Revision

Week (15) Class test

الفصل الدراسي السادس

Microbiology -4

Course title : Medical Virology

Intended term : term (6)

Course duration : 15 weeks

Lectures : 2 hrs /week duration 15 week

Practical : 3 hrs /week duration 15 week

Credit hours: 3 hours

Rationale

This course is intended for medical laboratory science students

General Objectives

By the end of this course medical laboratory students should be able to :

1. Know the basic features and nature of bacteria and other micro-organisms

2. Understand the morphology classification growth , genetics and nutrition of media bacteria .

3. know the basis of safety in microbiology as well as the source of laboratory infections , principles of good laboratory practices , personal safety precautions , and WHO standards for microbiology safety .

4. Know how to sterilize and disinfect glassware and materials used in the laboratory .

5. Understand the principles of instrumentation employed in microbiology laboratory .

Course contents

Week (1)

Introduction to medical viruses / General properties of viruses

Week (2)

Viral structure / Viral classification

Week (3)

Pathogenicity of medical viruses / Vital genetic and replication

Week (4)

Collection , transport and storage of viral specimens

Laboratory diagnosis of viral infection

Week (5)

Virus isolation / Cell culture techniques

Week (6)

Adenoviruses

Week (7)

Rotaviruses

Week (8)

Arthropod-borne virus (1) / Arthropod-borne virus (2)

Week (9)

Influenza viruses / Parainlfuenza viruses

Week (10)

Arboviruses / Measles and Rubella viruses

Week (11)

Enteroviruses (1) / Enteroviruses (2)

Week (12)

Poxviruses / Oncogenic viruses

Week (13)

Rabies viruses / Laboratory diagnosis of rabies

Week (14)

Hepatitis  /Laboratory diagnosis of viral hepatitis

Week (15)

HIV virus / AIDS

Practice

Week (1) Biosafty level and biosaftycabinate in virology lab

Week (2) Specimen processing for viral diagnosis

Week (3) Diagnostic method in virology direct diagnosis

Week (4) Virus isolation cell culture indirct method

Week (5) Cytopathic effect

Week (6) Virus isolation embryonated eggs

Week (7) Heamoagglutinationtesr

Week (8) Haemoagglutination inhibition

Week (9) Serology test ELISA test

Week (10) Polymerase chain reaction (PCR)

Week (11) Western blot techniques

Week(12) Immunoflourecence techniques

Week (13 ) Test class

Week (14 ) Presentation 

Clinical chemistry -4

Course Title: plasma lipids& body fluids and electrolytes

Course Semester: 6

Credit hours: 3

Prerequisites:  Study the following curses:

  1. General and analytical chemistry
  2. Biochemistry
  3. Introduction to clinical chemistry
  4. Physiology

Course duration: (14-16 week)

Course description:

Classification and function of lipids, metabolism and disorders of triglycerides and cholesterol, classification, functions, metabolism and disorders of lipoproteins, 24 hours urine analysis, water and electrolytes regulation, sodium, potassium, flame photometry, formation and handling of cerebrospinal fluid (CSF), biochemical investigation of CSF and other fluids, hydrogen ion homeostasis and disturbance of acid-base balance.

Course objectives:

At the end of this course, the students should able to:

Course contents (topics):

Theory:

  1. Lipids classification and functions
  2. Cholesterol metabolism and disorders
  3. Triglycerides metabolism and disorders
  4. Lipoproteins metabolism
  5. Lipoproteins disorders
  6. Water and electrolytes regulation: Sodium
  7. Water and electrolytes regulation: Potassium
  8. Electrolytes regulation: chloride, bicarbonate, magnesium
  9. Cerebrospinal fluid (CSF) formation and handling
  10. Biochemical investigation of CSF
  11. Ascetic, plural, synovial, amniotic & semen fluids
  12. Flame photometry
  13. Hydrogen ion homeostasis
  14. Disturbance of acid – base balance

Practical:

  1. Serum total cholesterol
  2. Serum triglycerides
  3. Serum HDL cholesterol
  4. Serum LDL cholesterol
  5. Flame photometer
  6. CSF analysis
  7. Reconcentration curve (creatinine)
  8. Reconcentration curve (protein)
  9. 24hr protein
  10. Serum magnesium
  11. Examination of serous fluids
  12. Examination of seminal fluid
  13. Examination of synovial fluid
  14. Examination of amniotic fluid


Parasitology-4

Course title: Medical  Mycology

Intended  term : (6)       

Coursduration : 12 weeks

Lectures : 2 hrs / week duration 12 weeks

Credit hour: 2 hours

Practical : 3 hrs / week  duration 12 weeks

Credit hours: 3 hours

This   cours is intended  for  medical  laboratory  sciences  students .

Instructional  methods :

Evaluation :

Final examination runs  by  internal  examiners.

Evaluation  consists  of :

General objectives :

By  the  end  of  this   course ,  medical  laboratory  students  should be   able to  :

1. Know the properties, features, and  pathogenesis of  fungal pathogens .

2. Perform the various technical methods used in the laboratory diagnosis of fungal infection

Specific   objectives:

1. Understand taxonomy & structure of medical fungi

2. Perform the laboratory diagnosis m, of cutaneous & able to perform diagnosis.

3. Understand general features of Malasszia furfur & able to   perform diagnosis

4. Perform  laboratory  diagnosis  of  Aspergillus, Histoplasam, Caniada, &Blastomyces .

Lectures

Week 1:introduction of fungi

Week 2:

Fungi  growth& classification

Week3 :

Pathogenicity , toxin production  &  allergies

Week 4 :

         Laboratory   diagnosis  & fungal  disease

Week5 :

Antifungal  therapy

Week (6)

superfacial mycosis

Week (6)

Malassezia   furfur

Week (7)

dermatophyte fungi 

Week (8)

dermatophyte fungi

Week (9)

dermatophyte fungi

Week (10)

subcutanousmycosimycetoma

Week (11)

mycetoma

Week (12)

revesion

Week (13 )

test class

Hematology -4

Intended term : (7)

Course duration :15 weeks

Study hours per week

Lecture :2 hours

Practical : 3 hours

Credit hours: 3 hours

Rational

This corusis intended for medical laboratory science students

General  objectives

By the end this course , the medical  laboratory students be able to understand the  component and  mechanism of the coagulation  system plus patheophysiology and  laboratory  diagnosis to be perform   laboratory investigation  that used  to  diagnose  the   diagnose or problems associated with   haemostasis

Specific   objectives

Upon the completion  of the cours the students should  be able  to :

Know  the component, promotion ,and regulation of coagulation system .

Know  the policy of  investigation   bleeding   tendency .

Perform  first line  investigation  (PT,APTT,and TT) and second line  investigation .

Instructional methods

Lectures

Laboratory Practical

Tutorial

Evaluations

Final examination  run by  internal examiners .

Evaluation  consist of :

M .C .Q:10%

Long essays : 20 %

Short questions  : 20%

Practical  : 40 %

Oral : 10%

Lectures

Week (1) introduction to coagulation disorders 

Week (2) platelet disorder                  

Week (3) coagulation disorder 

Week (4) acquired coagulation disorder

Week (5) thrombosis

Week (6) tutorial 

Week (7) class test 

Week (8) benign WBCS disorder

Week (9) introduction to leukaemia and acute myeloid leukemia

Week (10) chronic myeloid leukaemia

Week (11) chronic lymphatic leukaemia

Week (12) multiple myeloma and lymphoma 

Week (13) tutorial

Week (14) test class 

Practical

Week (1)

          Red Introductory laboratory , Objectives , Restriction , and plan

Week (2)

          Preparation of reagents 

Week (3)

          ABO grouping (direct and indirect) , Slide & Tube methods

Week (4)

          Rhesus phenotype and genotyping 

Week (5)

          Coombs’ test – Direct Coombs’ test – Indirect Coomb’s test

Week (6)

          Du method

Week (7)

          Quality control

Week (8)

          Blood bank techniques : Saline technique

Week (9)

          Blood bank techniques : Albumin technique

Week (10)

          Blood bank techniques : Enzyme technique

Week (11)

          Cross-matching : Direct (forward) and Indirect (reverse) cross-matching

Week (12)

          Antibody screening

Week (13)

          Antibody identification

Week (14) Antibody titration

Histopathology -4

Title of the course:        Cytopathology 1 

Intended term:     six

Course duration: 16 weeks.

Study hours per week: (2 theory + 2 practical).

Credit hours:3

Pre-requisite course:  Student should know and study Specific objects and practical course in term three and four and five

Course description :

        At the end of this course medical laboratory student should demonstrate knowledge of Cytology definition, types of cytological specimen, preparation of slide for microscopic studies, stains used and should be able to describe and identify normal and abnormal cellular changes in cytological samples of female genital tract under the microscope.

Specific objective:

Upon the completion of this course the student should be able to:

1- Discuss the aim, history of cytology and types of cytological specimen.

2- Know the theoretical and practical aspects of collection, processing, fixation and preservation of different types of biological specimen for cytology analysis.

3-   Know the theoretical and practical aspects for different staining methods of cytological smears

4- Know the theoretical and practical aspects for demonstration of sex chromatin, bar bodies in buckle smears and blood films

5- Describe and identify normal cellular component of cervical smears

6-Explain hormonal changes of females and their effect on cervical cytology.

7- Describe and identify abnormal cellular component of cervical smears

8- Discuss cervical screening program and adjacent test of HPV.

1-lectures

LecturesWeeks
The study of basic concepts and history of Cytology 1
Collection and Preparation of Samples  ( Fixation, fixatives for cytological samples, liquid base versus conventional)2
Collection and Preparation of Samples  (specimen adequacy, female genital tract)3
Collection and Preparation of Samples  (Respiratory system,  Urinary System , GIT, body fluid and serous effusion)4
Collection and Preparation of Samples  (FNA, cell block, mailing of cytology sample)5
Staining – Principles, Preparation of reagents, techniques  (H&E, Papanicolaou’s stain ,  May – Grunewald Giemsa stain , diff quick)6
Anatomy, histology, physiology and normal cytology of the female genital tract7
Hormonal  Cytology: (Correlation of structure of female genital tract & ovarian hormones – hormonal influences on cytology)8
Hormonal  Cytology  (Various Cytological indices  eg: Maturation Index  Karyopyknotic Index , Maturation Value)9
Infections and inflammation of female genital tract, 10
Human Papilloma virus correlation for neoplasm’s , HPV vaccination program11
Dyskaryosis or Dysplasia (Low grade, High grade of squamous intra epithelial lesions), Ca-in-situ, sq. Cell carcinoma and adeno-carcinoma of endocervix.12
Radiation and contraceptive effects on cells13
Endometrium (normal and abnormal conditions) ,other female genital neoplasm’s (ovarian, valve, vagina and fallopian tubes)14
Cytological screening of cervical cancer and other organ screening programs, Evaluation and follow-up)15
Report and Bethesda system16


2-Practical sessions

PracticalWeeks
Preparation of cytological fixatives1
Sample collection and processing (buckle smear, cervical smear, urine sample, sputum, body fluid)2
Staining of cytological sample (Harris hematoxylin and eosin)3
Staining of cytological sample (Papanicolau stain)4
Staining of cytological sample (May – Grunewald Giemsa stain)5
Staining of cytological sample (Diff quick)6
demonstration of sex chromatin, barr bodies in buckle smears and blood films7
Morphology of normal cervical pap smear8
Morphology of cervical cells in different hormonal stages and maturation index9
Morphology of inflammatory cells  and infections in cervical pap smear10
Morphology of abnormal cervical pap smear Dyskaryosis (Low grade , High grade of squamous intra epithelial lesions ), 11
Sqa Cell carcinoma and adeno-carcinoma of endocervix)12
Morphology of other female genital tract neoplasm’s13
Radiation changes14

Laboratory management & Quality assurance

Intended term : (7)

Course duration :15 weeks

Lecture :2 hours

Credit hours: 2 hours

Rational

This course is intended for medical laboratory science students

General objectives

By the end this course , the medical  laboratory students be able to understand the  component and  of quality control and  laboratory managements in order to perform true   laboratory investigation  results .

Specific   objectives

Upon the completion of the course the students should be able to:

1- Know the component, promotion, and procedures of quality control.

2-Know the policy of the laboratory investigations.

3- Know how to minimize the lab errors results.

Instructional methods

Lectures

Laboratory Practical

Tutorial

Evaluations

Final examination runs by internal examiners.

M .C .Q

Long essays

Short questions 

Oral

Lecture

Week (1)    

Introduction to quality control & quality assurance.

Week (2)              

Importance of quality control.

Week (3)              

Internal and external quality control

Week (4)              

Types of control materials

Week (5)              

Types of errors

Week (6)              

Rejection criteria

Week (7)              

Specimen management

Week (8)              

Choice of method

Week (9)              

Reliability of test results (Accuracy &precision)

Week (10)            

SOPS (Standard Operating Procedures)

Week (11)            

Quality control in microbiology.

Week (12)            

Quality control in histopathology.

Week (13)            

Quality control in hematology.

Week (14)            

Quality control in Parasitology.

Week (15)

Quality control in clinical chemistry.

Pharmacology

Course title: Introduction to pharmacology

Intended term : (6)

Course duration :15 weeks

Study hours per week

Lecture :2 hours

Credit hours  : 2 hours

Rational

This course is intended for medical laboratory science students

General Objectives

By the end of this course, the student is able to:

1- Know the mechanism of drug interaction and their effects.

2- Understand the basis of action of antimicrobial drugs, the pattern of bacterial resistance, and the methods of antimicrobial drug action.

3- Know the laboratory methods used for sensitivity test of isolated bacteria

Specific Objectives

By the end of this course, the student should be able to:

1- Understand the basic principles of the action of drugs and their effects in the body.

2- Understand the basic principles of drug metabolism in the human body.

3- Understand the basic principles of drug toxicity.

4- Understand the modes of action of antimicrobial drugs and the procedures of sensitivity testing.

Instructional methods

Evaluation

Final examination runs by internal examiners

Lectures

Week (1)

Definitions of terminologies used.

Week (2)

Sources of drugs.

Week (3)

Nomenclature of drugs.

Week (4)

Types of drugs.

Week (5)

Routes of administration.

Week (6)

Pharmacokinetics

Week (7)

Pharmacodynamics

Week (8)

Targets of drug action

Week (9)

Factors modifying dosage and drug action

Week (10)

Classification of drugs

Week (11)

Drugs acting on autonomic nervous system

Week (12)

Drugs affecting hematopoietic system

Week (13)

Tutorial

الفصل الدراسي السابع

مواد لكل تخصص

Genetics

Intended term : (7)

Course duration :15 weeks

Study hours per week

Lecture :2 hours

Credit hours: 2 hours

Rational

This course is intended for medical laboratory science students

General objectives

By the end this course, the medical laboratory students be able to understand the concepts and fundamental information   of geneticsand human molecular genetics and gene diseases.

Specific   objectives

Upon the completion of the course the students should be able to :

Know human genetics and related knowledge of human genetic normal and abnormal function.

Know genetic disease that exist and investigation could be done .

Know genetic basis of oncology, hematological and other genetic disorders.

Instructional methods

Lectures

Laboratory Practical

Tutorial

Evaluations

Final examination  run by  internal examiners .

Evaluation  consist of :

M .C .Q:10%

Long essays : 20 %

Short questions  : 20%

Practical  : 40 %

Oral : 10%

Lectures

Week (1)

Introduction

Week (2)

Genetic material & chromosome structure                        

Week (3)

Cell division &crossing over  

Week (4)

Replication

Week (5)

Transcription

Week (6)

Genetic code and translation

Week (7)

Mutation

Week (8)

Mendelian genetics

Week (9)

Chromosomal inheritance and abnormalities

Week (10)

Genetic diversity

Week (11)

Population genetics

Week (12)

Gene mapping

Week (13)

Genetic diseases -1

Week (14)

Genetic diseases-2

Week (15)

Human gene therapy

Forensic & Toxicology laboratory

Course Title :Forensic  laboratory

Credit hours: 2

Contact hours: 2hr per week

General Course Objectives:

(General learning outcomes expected from this course)

To acquire basic medical and laboratory knowledge and skills concerning the main areas and branches of forensic medical sciences and toxicology.

Specific Course Objectives:

By the end of this course the student should be able to:

  1. Discuss and describe the histological, serological and chemical tests used in the establishment of identity of human remains.
  2. Discuss post-mortem chemistry and the use of vitreous humour chemistry in timing death.
  3. Describe the role of forensic laboratory scientist in crime scene investigation.
  4. Describe types of wounds and discuss diagnosis and dating of wounds byhistological andhistochemical methods.
  5. Discuss laboratory aspects of injuries by burns, scalds, electrification and lightning.
  6. Define drowning, discuss and describe chemical and histological changes in the blood in drowning and the role of diatoms in  the diagnosis of drowning.
  7. Discuss and describe the laboratory intervention in different types of sexual offences.
  8. Discuss and describe the laboratory aspects of deaths associated with pregnancy and abortion and diagnosis of abortificiant drugs in living victims.
  9. Discuss the laboratory finding of sudden death.
  10. Discuss and describe the concept of the fatal dose, variations in published fatal poison concentrations, the collection of autopsy samples fortoxicological analysis, containers for toxicology samples, preservatives in samples, the site of sampling for toxicological analysis and the technique of obtaining autopsy samples.
  11. Discuss forensic aspects of alcohol.
  12. Describe the causes and blood analysis in carbon monoxide poisoning.
  13. Discuss agrochemical poisoning.
  14. Describe the laboratory role in poisoning by medicine.
  15. Discuss lab analysis of poisoning and death due to narcotic andhallucinogenic drugs.
  16. Identify and Discuss laboratory aspects of corrosive and metallic poisoning.
  17. Describe technical methods used for forensic purposes like diatom technique in suspected drowning and samples and controls needed for DNA profiling.
  18. Describe the laboratory tools used in forensic science.

Course Structure:

  1. Lectures, Seminars, Tutorials, etc.
  2. Practical:
  3. Other Clinical Activities:(e.g. journal clubs, laboratory seminars etc. Specify frequency and suggested topics; problem-based learning session).
  4. Continuous evaluation:
  5. Number of Hours and Methods of Teaching:
  6. Evaluation Methods:

Assessment:

  1. Written Examination:
    1. Practical Examination:

Lectures

Week (1)

Introduction to forensic science-Nature need and function

Week (2)

Identifying Human Remains

-Identifying the Body: Human or Nonhuman?

-Skin Coloration

-Defensive Wounds and Other Visible Marks

Week (3)

Post-mortem lab investigation

-Post-mortem chemistry

Week (4)

The wounds and injuries

-types of wounds 

-Diagnosis and dating of wounds byhistological andhistochemical methods

Week (5)

Laboratory aspects of injuries by burns, scalds, electrification and lightning

Week (6)

Immersion deaths

-Chemical and histological changes in the blood in drowning

-The role of diatoms in the diagnosis of drowning.

Week (7)

The laboratory intervention in different types of sexual offences

Week (8)

-Interpretation of minimal findingseg blood, saliva, etc. -Tests for semen.

Week (9)

Forensic Serology-The Nature of Blood-Immunoassay Techniques-Forensic Characterization of Bloodstains-Stain Patterns of Blood-Principles of Heredity-Forensic Characterization of Semen

Week (10)

The Indispensable Forensic Science Tool -Medico legal significance-DNA technique -DNA finger print

Week (11)

The concept of the fatal dose, variation sin published fatal poison concentrations, the collection of autopsy samples fortoxicological analysis, containers for toxicology samples, preservatives in samples, the site of sampling for toxicological analysis and the technique of obtaining autopsy samples.

Week (12)

The Role of the Toxicologist-Techniques Used in Toxicology-Toxicology of Alcohol -The Significance of Toxicological Findings

Week (13)

-Poisoning and death due to narcotic andhallucinogenic drugs.-Poisoning by medicine.-Corrosive and metallic poisoning.-Agrochemical poisoning

Week (14)

Revision

Week (15)

Class test

Research methodology

Course title: Research methodology

Intended term : (7)

Course duration :15 weeks

Study hours per week

Lecture :2 hours

Credit hours  2 hours

Rational

This course is intended for medical laboratory science students

General objectives

By the end this course, the medical laboratory students be able to understand the concepts and fundamental information and concepts research.

Specific   objectives

Upon the completion of the course the students should be able to:

1-Know how to perform research proposal and objectives.

2- Know how to write literature review, data collection and data analysis.

3-Know the general ethics of the research.

Instructional methods

Lectures

Tutorial

Evaluations

Final examination runs by internal examiners.

M .C .Q:10%

Long essays : 20 %

Short questions  : 20%

Practical  : 40 %

Oral : 10%

Lectures

Week (1):

Introduction

Week (2):

Research objectives

Week (3):

       Variables

Week (4):

         Research proposal

Week  (5) :

         Literature review

Week (6)

       Study design

Week (7)

       Sampling

Week (8)

         Data collection

Week (9)

         Data analysis

Week (10)

        Research ethics

Week (11)

       Revision

Week (12)

Tutorial

Week (13)

    Test class

Molecular biology -2

Course title: Molecular biology

Intended term : 7

Course duration : 15 weeks

Credit hours : 2

Practical: 3hrs

Rational

This course is intended for medical laboratory science students

General Objectives

By the end of this course medical laboratory students should be able to :

Lecture

Week (1)          Extraction of nuclia acid DNA extraction   

Week (2)           RNA extraction

Week (3)           Agarose electrophoresis techniques

Week (4)          Application of molecular biology (PCR TECHNIQUES )

Week (5)          Other type pf PCR

Week (6)           DNA sequencing  

Week (7)           Cloning technique 

Week (8)           Application of recombinant technology

Week (9)           Hyberdization technique

Week (10)         Hybridization technique                                     

Week (11)         Restriction enzyme

Week (12)         Chromosome structure

Week (13)         Chromosome disease

Week (14)         Revision

Week (15)        Test class

Clinical chemistry -5

Course Title : Enzymology & Endocrinology

Course Smester : 7

Credit hours: 4

Prerequisites: study the following courses:

5- General and analytical chemistry

6- Biochemistry

7- Introduction to clinical chemistry

8- Physiology

Course duration : ( 14- 16 week)

Course description:

General properties and definitions, enzyme classification and nomenclature, enzyme kinetics “catalytic mechanism of enzymes, factors that influence Enzymatic reactions, measurement of Enzyme activity. Calculation of enzyme activity, measurement of enzyme mass. enzyme as reagents” enzyme of clinical  significance :creatine kinase lactate dehydrogenase , Aspartate Aminotransferase ,Alanine Aminotransferase , Alkaline phosphatase , Acid Phosphatase , ϒ Glutamyltransferase , Amylase , Lipase G-6-PD. Introduction to hormones and pituitary function , hypothalamic hormones , anterior pituitary hormones , posterior pituitary hormones , adrenal function , gonadal function , thyroid gland , parathyroid function .

Course objectives:

By the end of this course, the students should able to :

  1. Define the term enzyme, including physical composition and structure .
  2. Classify enzymes according to the international Union of Biochemistry (IUB).
  3. Discuss the different factors affecting the rate of an enzymatic reaction .
  4. Explain enzyme kinetics including zero – order and first – order kinetics .
  5. Explain why the measurement of serum enzyme levels is clinically useful .
  6. Discuss the tissue sources, diagnostic significance and assay .
  7. Evaluate patient serum enzyme levels in relation to disease states .
  8. Define hormones .
  9. Classify and apply hormones in clinical chemistry .
  10. Discuss hormones action and regulation .
  11. Discuss pituitary , thyroid , parathyroid and adrenal glands .
  12. Understand the difference between primary and secondary deficiency states.
  13. Describe steroid biosynthesis , regulation ,and action according to anatomic location within the adrenal gland .
  14. Describe the appropriate laboratory testing protocol to effectively evaluate or monitor patients with suspected gonadal disease .

Course contents (topics ):

Theory :

  1. General properties and definitions, enzyme classification and nomenclature .
  2. Enzyme kinetics ( catalytic mechanism of enzymes , factors that influence enzymatic reactions ).
  3. Measurement of enzyme activity .
  4. Enzyme kinetics ( calculation of enzyme activity , measurement of enzyme mass , enzymes as reagents ).
  5. Enzymes of clinical significance ( creatinine kinase , lactate dehydrogenase ,Aspartate Aminotransfersase Alanine Aminotransferase ).
  6. Enzymes of clinical significance( Alkaline phosphatase , Acid Phosphatase ,  ϒ Glutamyltransferase , Amylase , Lipase , Glucose -6-Phospatase , Dehydrogenase ).
  7. Plasma enzymes patterns in disease ( GIT , cardiac, liver enzymes ).
  8. Definition , regulation and classification of hormones ( definition , chemical , nature and classification of Hormones ).
  9. Hormonal assay (classical assays , Immunologic assay , Fluorescent technique , High-performance Liquid Chromatography and Colorimetry ).
  10. Hypothalamus and pituitary glands (Anterior pituitary hormones (Growth hormone , Prolactin ).Posterior pituitary hormones (ADH, Oxytocin ) ).
  11. Thyroid hormones ( Thyroid hormones (T3 and T4) , Hyperthyroidism , Hypothyroidism and Thyroid Stimulating Hormones).
  12. Parathyroid gland ( Parathyroid hormones , Hyperparathyroidism , Hyperparathyroidism).
  13. Adrenal cortex hormones ( Adrenal Cortex hormones (Aldosterone, cortical )).
  14. Adrenal medulla  hormones (Adrenal medulla  hormones( Adrenaline and Nor adrenaline)).
  15. Reproductive system and Sex hormones ( Sex hormones , (weak androgens , Testosterone , Dehydroepiandrosteron )).

Practical :

  1. Serum AST estimation .
  2. Serum ALT estimation .
  3. Serum ASP estimation .
  4. Serum GGT estimation .
  5. Serum Amylase  estimation .
  6. Serum Lipase  estimation .
  7. Serum CPK estimation .
  8. Serum LDH estimation .
  9. Principle and procedure of ELLZA .
  10. Serum TSH estimation .
  11. Serum T4 estimation .
  12. Serum T3 estimation .
  13. Serum FSH estimation .
  14. Serum LH estimation .
  15. Serum PRL estimation .
  16. Serum and urine cortical  .
  17. Serum testosterone  .
  18. Serum total HCG and beta HCG.
  19. Serum progesterone.

Hematology -5

Course title: Hematology

Intended  term : (7)

Coursduration : 15 Weeks :

Study  hours  per week :

Lecture  : 2 hours

Practical : 3 hours

Credit  hours  : 4 hours

Rational

This coursis  intended  for  medical  laboratory  science  students

General  objectives

By  the  end  of this  course , the medical  laboratory  students  should be  able  to  understand  pathophysillogy  and  laboratory  diagnosis  of multiple  myeloma, lymphoma, DIC,haemophilia  and  Von  willebrand  disease . Further  more  he  should  also be  able  to  perform  laboratory  investigations  that  confirm  the  diagnosis  of these  haematological  disorders .

Specific  objectives

Upon  the  completion  of  the  course  the  students  should  be  able  to :

Know  the  pathophysiology  and laboratory  diagnosis of DIC,Haemophilia, and  Von willebrand  disease .

Know the   definition , pathophysiology , laboratory   diagnosis  of multiple  myeloma  and  lymphoma .

Know  principles , type  and  operation of  automation  in haematology , in addition  to  radioisotops.

Know  definition , pathophysiology  and  laboratory diagnosis  of  multiple   myeloma  and  lymphoma.

Instructional  methods

Lectures

Laboratory  Practical

Tutorials

Evaluations

Final examinations  run  by  internal  examiners

Evaluation  consits  of :

M.C.Q :10 %

Long essays : 20 %

Short  questions : 20 %

Practical : 40%

Oral : 10 %

Course description

The  cours  covers  the  followng  subjects :

Lectures

Week (1)

Platelets function tests

Week (2)

Disseminated intravascular Coagulation (DIC)

Definition & Causes   Laboratory diagnosis

Week (3)

Myelo fibrosis

Week (4)

 Coagulation   factors  assay

Week (5)

Investigation ofcirculating anticoagulants “inhibitor”

Inhibitor screeningQuantitative measurement of factor Viii-c inhibitors

Week (6)

 Clot solubility test for factor  Xiii

Principle and procedure Interpretation of results

Week (7)

Measurements of protein S Functional assay E LISA

Week (8)

Measurement of protein C

Cloning  based  protein  C assay

Week (9)

Monitoring of  oral  anticoagulants

Week (10)

Radio  isotopes Definition  and  source  of  radionuclide Application  in  hematology

Week (11)

 Radioisotopes

Determination  of  blood   volume , plasma volume  and red  cell  mass

Estimation  of red  blood  cell  lifespan .

Week (12)

Automation  in blood  cell  acount  .Principles  of  instruments   Types  and  operation

Week (13)

Automation  in hemostasis Principle of  coaguaometerTypes  and operation

Week (14)

Multiple  myeloma Definition  and  pathophysiology Laboratory diagnosis

Week (15)

 Lymphoma

Definition  andpathophysiplogy Laboratory  diagnosis

Practical

Week (1) First line  tests

Week (2) Correction  tests

Week (3) Platelet  function  tests

Week (4) Platelet  function tests

Week (5) Investigation  of  the  inhibitors

Week (6) Fibrinogen  estimation

Week (7) Clot  solubility test 

Week (8)  Protien  S  estimation

Week (9) ProtienC  estimation

Week (10) Vitamin-k- estimation

Week (11) Radioisotopes

Week (12) Radioisotopes

Week (13) Autmation  “Culter”

Week (14)  Automation  “coagulometer”

Week (15)   Kleihauer   test

Histopathology -5

Title of the course:        Cytopathology ‖

Intended term:     7

Course duration: 14 weeks.

Study hours per week: (2theories + 2 practical).

Credit hours: 4

Course description:

         This course will provide the student with the basic knowledge of the theory and practical aspect in the diagnosis of tumor cells and non-malignant conditions in non-gynecologic cytological samples under the light microscope.

Specific objective:

Upon the completion of this course the student should be able to:

1- Discuss and identify Anatomy, Histology, physiology and normal cytology of the respiratory tract

2- Discuss and identify Cytology of non-malignant and malignant conditions of respiratory tract

3- Discuss and identify Anatomy, Histology, physiology and normal cytology of the urinary system

4- Discuss and identify Cytology of non-malignant and malignant conditions of urinary tract

5- Discuss and identify Anatomy, Histology, physiology and normal cytology of the oral cavity and Gastro-Intestinal tract.

6- Discuss and identify Cytology of non-malignant and malignant conditions of oral cavity and gastrointestinal tract

7- Discuss and identify Cytology of non-malignant and malignant conditions of body fluids

8- Discuss and identify Anatomy, Histology, physiology and normal cytology of breast.

9- Discuss and identify Cytology of non-malignant and malignant conditions of fine needle (FNAC) aspiration and nipple discharge of breast.

10- Discuss and identify Anatomy, Histology, physiology and normal cytology of lymph node and thyroid

11- Discuss and identify Cytology of non-malignant and malignant conditions of lymph node and thyroid

12- Discuss types of Automation in Cytopathology lab

13- Quality control in Cytopathology lab

  1. Lectures:
LecturesWeeks
Anatomy, Histology, physiology and normal cytology of the respiratory tract1
Cytology of  non-malignant and malignant conditions of respiratory tract2
Anatomy, Histology, physiology and normal cytology of  the urinary system3
 Cytology of  non-malignant and malignant conditions of urinary tract4
Anatomy, Histology, physiology and normal cytology of  the oral cavity and Gastro-Intestinal tract5
Cytology of  non-malignant and malignant conditions of oral cavity and gastrointestinal tract6
 Cytology of  non-malignant and malignant conditions of body fluid, effusions  & C S F7
  Anatomy, Histology, physiology and normal cytology  of breast8
Cytology of  non-malignant and malignant conditions of fine needle (FNAC) aspiration and nipple discharge of breast9
Anatomy, Histology, physiology and normal cytology of lymph node and  thyroid10
Cytology of  non-malignant and malignant conditions of lymph node and  thyroid11
types of Automation in  Cytopatholgy lab ( Flow Cytometry , Image Analysis,Principles, equipment, procedure and evaluation)12
Ancillary tests in cytology13
Quality control in cytopathology lab14

2-Practical sessions

PracticalWeeks
Screening cervical smears for cervical cancer1
Normal ,inflammation and abnormal cytology of respiratory tract2
Normal ,inflammation and abnormal cytology of urinary tract3
Normal ,inflammation and abnormal cytology of oral cavity and gastrointestinal tract4
Normal ,inflammation and abnormal cytology of body fluid, effusions  & C S F5
Normal  cytology of breast FNA and nipple discharge6
Inflammation in   cytology of breast FNA and nipple discharge7
Abnormal cytology of breast FNA and nipple discharge8
 Normal ,inflammation and abnormal cytology lymph node9
Normal ,inflammation and abnormal cytology thyroid gland10
Flow cytometry operation, interpretation of result11

Microbiology -5

Course title: Medical Mycology

Intended term: (7)        

Course duration: 14 weeks

Lectures: 2hrs / week duration 14 weeks

Credit hour: 4 hours

Practical: 3hrs / week duration 14 weeks

Credit hours: 2 hours

This   cours is intended  for  medical  laboratory  sciences  students .

Instructional  methods :

Evaluation :

Final examination runs  by  internal  examiners.

Evaluation  consists  of :

General objectives :

By  the  end  of  this   cours ,  medical  laboratory  students  shoud be   able to  :

1. know the properties , features, and  pathegeneis of  fungal pathogens .

2. Perform the variostechicalmetheods used in the laboratory  diagnosis of fungal infection

Specific   objectives :

1. Undestandtazonomy& structure of medical fungi

2. Perform the laboratory diagnosis m, of  cutaneous& able to  perform  diagnosis .

3. Understand  general  features  of  Malasszia  furfur  &  able to   perform  diagnosis

4. Perform  laboratory  diagnosis  of  Aspergillus, Histoplasam, Caniada, &Blastomyces .

Week 1 :

Week 2 :

Week3 :

Week 4 :

Week5 :superfacial mycosis

Week 6 :

Week 7 :

Week 8 :syetemic mycosis

Week 9 :

Week 10 :opportunistic mycosis

Week 11 :

Week (12)

Asperigellus  species

Week (13)

        –   Presentation

Week (14)

       –  Presentation

Week (15)

        – Class test

Practicle

Week(1)

Lab safty in mycology lab

Week(2)

Specimen collection for fungial diagnosis

Week (3)

KOH and lactophenol cotton blue

Week (4)

Preparation of culture media and type for culture of fungal infection

Week (5)

         Lab diagnosis of superficial mycosis

Week (5)

       Lab diagnosis of cutanous mycosis

Week (6)

        Lab diagnosis of mycetoma infection

Week (7)

        Lab diagnosis of systemic mycosis

Week (8)

        Lab diagnosis of candida albicans

Week (9)

       Lab diagnosis of Cryptococcus neofoemans

Week (10)

      Lab diagnosis of aspergulusspp

Week (11)

      Presentation

Week (12)

       Revision

Week (13)

      Test class

Week (14)

        Last examination

Parasitology -5

Course title: medical entomology

Intended term: (7)

Course duration: (15) weeks

Credit hours: 4 hours

Rationale

This course is intended for medical laboratory science students

General Objectives

By the end of this course , medical laboratory students should be able to :

Specific Objectives

By the end of this course the students should be able to :

Instructional method

Course contents

Week (1)

          Definition and scope of medical entomology

Disease transmission

Week (2)

          Classification and characteristics of arthropods

Arthropod development

Week (3)

          External morphology of insects

Week (4)

          Internal structure of insect

Week (5)

          Order Diptera

Suborder Nematocera

Week (6)

          Family Culicidae – Mosquitoes

Week (7)

          Control of mosquitoes (Seminar)

Week (8)

          Family Psychodidae – Sand fly

Week (9)

          Family Simuliidae – Black fly

Family Ceratopogonidae

Week (10)

          Family Tabanidae – Horse fly

Family Chrysopidae – Deer fly 

Week (11)

          Family Muscidae – House fly

Family Glossinidae – Tsetse fly

Week (12)

          Family calliphridae

Family Oestridae

Mayiasis

Week (13)

          Order Siphonaptera – Flaes

Week (14)

          Order Anopliura – Lice

Order Hemiptera – Ticks

Week (15)

          Class Arachnida

Acarini – Mites

Practical

Week (1)

          Classification and genera Visual presentation

Properties of arthropods

Week (2)

Morphhology of insect             Demonstration

Week (3)

          Entomology methods                Practical

Week (4)

          Collection and preservation of arthropods

Week (5)

          DemonstrationMosquitoes – Anophelinie

Week (6)

          Mosquitoes – Culicine

Week (7)

          House fly

Week (8)

Practical Sand fly

Week (9)

          Demonstration Black fly

Week (10)

          Ticks

Week (11)

          – Tsetse fly

Week (12)

          Tabanid fly

Week (13)

          Flea

Week (14)

          Lice, mite

Week (15)

Revision

الفصل الدراسي الثامن

Biostatistics

Course title: Biostatistics

Intended term: (8)        

Course duration: 14 weeks

Lectures: 2hrs / week duration 14 weeks

Credit hour: 2 hours

Credit hours: 2 hours

This   course is intended for medical laboratory sciences students.

Instructional methods:

Evaluation:

Final examination runs by internal examiners.

Evaluation consists of:

Lectures

Week 1 :Introduction

Week 2:       Defining data

Week3:       Display of data

Week 4:       Mean median mode

Week5:       Measures of variation

Week 6:       Normal distribution

Week 7:       Sample and sampling

Week 8:       Analysis

Week 9 :      Tutorial

Week 10 :    Rivision

Week 11 :    Tutorial

Week (12)   Class test

Medical Ethics

Course title: Medical Ethics

Intended term: (8)        

Course duration: 14 weeks

Lectures: 2 hrs / week duration 14 weeks

Credit hour: 2 hours

This   course is intended for medical laboratory sciences students.

Instructional methods:

Evaluation:

Final examination runs by internal examiners.

Evaluation consists of:

Lectures

Week 1 :

Introduction

Week 2:

     Basic Responsibilities & composition

Week3:

Regulation –Training –Term of reference

Week 4:

Decision making process

Week5:

Record keeping & special consideration

Week 6:

General ethical issues

Week 7:

Specific principles of clinical evaluation

Week 8:

clinical evaluation of Drugs- Devices –Diagnostic –Vaccines  

Week 9 :

clinical evaluation of traditional

Week 10 :

Statements of specific principles for Epidemiological studies

Week 11 :

Tutorial

Week (12)

       Revision

Week (13)

Class test

Diagnostic Hematology

Course title: Diagnostic Hematology

Intended  term : (8)

Course duration : 15 Weeks :

Study  hours  per week :

Lecture  : 2 hours

Practical : 3 hours

Credit  hours  : 4 hours

Rational

This coursis  intended  for  medical  laboratory  science  students

General  objectives

By  the  end  of this  course , the medical  laboratory  students  should be  able  to  understand  pathophysillogy  and  laboratory  diagnosis  of multiple  myeloma, lymphoma, DIC,haemophilia  and  Von  willebrand  disease . Further  more  he  should  also be  able  to  perform  laboratory  investigations  that  confirm  the  diagnosis  of these  haematological  disorders .

Specific  objectives

Upon  the  completion  of  the  cours  the  students  should  be  able  to :

Know  the  pathophysiology  and laboratory  diagnosis of DIC,Haemophilia, and  Von willebrand  disease .

Know the   definition , pathophysiology , laboratory   diagnosis  of multiple  myeloma  and  lymphoma .

Know  principles , type  and  operation of  automation  in haematology , in addition  to  radioisotops.

Know  definition , pathophysiology  and  laboratory diagnosis  of  multiple   myeloma  and  lymphoma.

Instructional  methods

Lectures

Laboratory  Practical

Tutorials

Evaluations

Final examinations  run  by  internal  examiners

Evaluation  consits  of :

M.C.Q :10 %

Long essays : 20 %

Short  questions : 20 %

Practical : 40%

Oral : 10 %

Course description

The  course  covers  the  following  subjects :

Lectures

Week (1)

Blood banking

Week (2)

Myeloproliferative disorders

Laboratory diagnosis

Week (3)

Hemophilia andVon willebrand disease

Hemophilia A , B and C

Week (4)

 Coagulation   factors assay

Week (5)

Quality control in hematology

Week (6)

Clot solubility  test  for  factor  Xiii

Principle and  procedure

Interpration  of  results

Week (7)

 Bone marrow

Week (8)

Measurement  of  protein C

Protac

Cloning  based  protein  C assay

Week (9)

Haemoparasites

Week (10)

Radio  isotopes

Definition  and  source  of  radionuclide

Application  in  hematology

Week (11)

Radioisotopes

HDN and HTR .

Week (12)

Automation  in blood  cell  acount  .

Principles  of  instruments  

Types  and  operation

Week (13)

Automation  in hemostasis

Principle of  coaguaometer

Types  and operation

Week (14)

Multiple  myeloma

Definition  and  pathophysiology

Laboratory  diagnosis

Week (15)

 Lymphoma

Definition  andpathophysiplogy

Laboratory  diagnosis

Practical

Week (1) First line  tests

Week (2) Correction  tests

Week (3) Platelet  function  tests

Week (4) Platelet  function tests

Week (5) Investigation  of  the  inhibitors

Week (6) Fibrinogen  estimation

Week (7) Clot  solubility test 

Week (8)  Protien  S  estimation

Week (9) ProtienC  estimation

Week (10) Vitamin-k- estimation

Week (11) Radioisotopes

Week (12) Radioisotopes

Week (13) Autmation  “Culter”

Week (14)  Automation  “coagulometer”

Week (15)   Kleihauer   test

Diagnostic Microbiology

Course title: Diagnostic Microbiology:

Intended  term : sems 8

Coursduration : 14 weeks

Lectures : 2 hrs / week duration 14 weeks

Practical : 3 hrs / week  duration 14 weeks

Credit hours: 4 hrs

Rationale

This   courseis intended for medical laboratory sciences students.

Instructional methods:

Evaluation:

Final examination runs by internal examiners.

Evaluation consists of:

Lectures

Week 1 :

Week 2 :

Week3 :

Week 4 :

Week5 :

Week 6 :

Week 7 :

Week 8 :

Week 9 :

Week 10 :

             Blood stream infection 

Week 11 :

Week 12 :

minor pathogenic bacteria

Week (13)

 Body fluid infection infection  Seminal fluid

Week(14)

        Synovial fluid

Week (15)

Practicle

Week (1)

Examination of urine specimen isolation and identification

Week (2)

Examination of stool specimen isolation and identification

Week (3)

Examination of sputum  specimen isolation and identification

Week (4)

Examination of ear swab specimen isolation and identification

Week (5)

Examination of eye swab specimen isolation and identification

Week(6)

Examination of wound swab  specimen isolation and identification

Week (7)

Examination of blood  specimen isolation and identification

Week (8)

Examination of CSF  specimen isolation and identification

Week(9)

Examination of throut and mouth  specimen isolation and identification

Week (10)

Examination of synovial fluid  specimen isolation and identification

Week (11)

Seminal specimen collection and properties

Week (12 )

Bacterial count

Week (13)

Sensitivity test

Week(14 )

Revision

Week (15)

Test class 

 Diagnostic Parasitology

Intended term  : 8

Credit hours : 4

The course consists of  three  modules :

  1. Diagnostic  Parasitology
  2. Clinical  Parasitology
  3. Immune  &  Molecular  Parasitology

Rationale

This  cours  is  intended  for   medical  laboratory  sciences  students (Medical  Parasitology )

General  objectives

By  the  end   of  this  course  medical   laboratory   science  students  should  be  able  to :

Instructional  methods

Evaluation

Final  examination  run  by  internal   and  external   examiner  consist of :

  1. Written  examination  of two   papers
  2. Paper  one : Advanced  parasitology (50% diagnostic  paraitology , 25% molecular  and  immune-parasitology)
  3. Paper two : (Medical  protzology 40% ,  medical  helminthology 40% , and  medical  Entomology 20%)
  4. Practical  examination   of  two  papers
  5. Paper one :  cases
  6. Paper two   OSPE   and  demonstration 
  7. Oral  examination
  8. Assessment  of  field   visits   and  seminars .

Final  evaluation

Diagnostic  parasitology  :

Duration  : 15 weeks

Credit  hours : 3 hrs

Specific  objectives

By the  end  of  this  cours  medical  laboratory   students  should  be  able  to :

Coruse  contents

Lectures  and  seminars

Week 1

        Host parsitereleationship (lecture)

Week 2

           Microscopy (light, phase, fluorescent,electronic) (tutorial)

Week 3

Corpologicalexamintaion  I(concerntration  techniques)(lecture)

Week 4

Corpological  examination 11(staining and  permanent mounts) .

Week 5

Heamatologicalexamination  of  protozoa

Week 6

Culture  technique I

Week 7

Culture  technique II(tutorials)

Week 8

laboratory  models (field  visits)

Week 9

Animal  inculation  (Field  visit)

Week 10

Recovery  of  parasites  from  aspirates, biopsies,and tissues (Tutorial)

Week 11

         Parasitology method  in  ecology  and  population  dynamics (Group discussion )

Week 12

Relevance  of  radiology  in the   diagnosis  of  parasitic  infections (Lecture)

Week 13

Value  of  research  in  understanding  medical  parasitology (Lecture)

Week 14

parasitological  survey  (molecular  epidemiology, sero-prevalence) – introduction  to bioinformatics

Week 15

Class  test

Practical

Week 1       

           Q .C measures  SOPs (group   discussion)

Week 2       

           Microscopy

Week 3       

stool  examination  (general)

Week 4       

staining  of  fecal  smears  and  prepration  of permanent mounts .

Week 5       

Techniques  used in  blood  for  parasitological  studies

Week 6       

Preprationof  culture  media I(3N)

Week 7       

Prepration  of culture  media  II

Week 8       

Breeding  and  handling  of  laboratory  models (field visit)

Week 9       

       Animal inoculation

Week 10     

             Processing of tissue and   anspirates  forparsitological studies (group work )

Week 11     

               Examination of water, soil , and other  environmental  specimens  (field visit)

Week 12     

           Demonstration of radilolgical images (seminar)

Week 13     

            Conducting field survey (field visit)

Week 14     

              Computer search and internet (group work)

Week 15     

        Class test

 Diagnostic Histopathology

Title of the course: advanced histo- technologies

Intended term:     8

Course duration: 14 weeks.

Study hours per week: (2 theory + 2practical).

Credit hours: 4

Pre-requisite course:

           Student should know and study Specific objects and practical course in term 2 up to 7

Course description:

         During this course, the student will study the theoretical and practical bases of immunohistochemistry and its application in pathology, immunofluorescence, enzyme-histochemistry, histotechnologies in neuroendocrine and neuropathology, tissue preparation for Electron Microscopy and its diagnostic application, as well as, tissue culture technologies. Also, the student will study the related tasks needed in the unit, e.g. photography, tissue microarray, laser micro dissection and plastic embedding Quality control and lab safety.

Specific objective:

Upon the completion of this course the student should be able to:

1- Discuss and demonstrate knowledge of the basic concepts of immunohistochemistry

2-Discuss and apply Immunohistochemical methods and protocols.

3- Discuss and demonstrate knowledge of quality control procedures in immunohistochemistry practice.

4-Discuss and demonstrate knowledge of immunohistochemistry application in pathology and tumor markers

5- Discuss and apply immunofluorescent techniques and demonstrate knowledge of their diagnostic applications in histopathology.

6- Discuss and apply neuroendocrine techniques and demonstrate knowledge of their diagnostic applications in histopathology.

7- Discuss and apply neuropathology techniques and demonstrate knowledge of their diagnostic applications in histopathology.

8- Discuss and apply techniques of tissue preparation for electron microscopy and demonstrate knowledge of its diagnostic applications in histopathology.

9- Discuss and apply tissue and cell culture techniques.

10- Discuss and demonstrate knowledge of lab safety protocols and quality control procedures in histopathology lab.

1-Lectures:

LecturesWeeks
Immunohistochemistry: introduction, basic concepts and principal, production of antibody monoclonal , polyclonal and labels1
Immunohistochemicalmethods : direct methods, indirect technique, bridge methods:  enzyme complex technique APA &APAAP, immunogold silver technique , avidin-biotin technique and others.2
Immunohistochemical methods: Antigen retrieval preservation of antigens, blocking background staining, dilution of immune serum\ antibodies, washes, incubationmethods, controls and general protocol.3
Immunohistochemistry Quality control: factors affecting staining and troubleshooting.4
Immunohistochemistry application in pathology: surgical pathology, infectious disease, brain disease, muscle disease and tumor markers (Intermediate filaments, epithelial markers, carcinomas, mesotheliomas, sarcomas, melanomas, lymphomas)5
Immunofluorescence: techniques, microscopy, quality control and diagnostic application in histopathology6
Enzymehistochemistry :Classification and nomenclature of enzymes, types of histochemical reaction7
Diagnostic application of enzyme histochemistry: Skeletal muscle biopsy, demonstration of mast cell and white cells of the myeloid series, detection of nerve and ganglia in suspected Hirschsprungs disease and other8
Neuroendocrine system: : components, pathology  and techniques of stainingcytoplasmic granules and organelles9
Histotechnologies in neuropathology: staining of component of  the nervous system (neurons, axons, fiber, myelin, neuralgias ) , handling and preparation of neuropathology specimens10
Electron microscopy: principles, structure and operation ,processing of a specimen to TEM(specimen handling, fixation, dehydration and clearing, Infiltration, embedding and sectioning) staining and sectioning faults causes and remedies11
diagnostic applications of electron microscopy: renal disease, malignant tumors, non-neoplastic diseases12
Lab safety and Quality control  in histopathology lab13
Over view on new  histotechnologies  and related tasks14


2-Practical:

PracticalWeeks
Preparation of coated slides1
Preparation of buffers2
Heat retrieving methods3
Enzyme retrieving methods.4
Immunohistochemistry preparation of solutions and target retrieval methods5
Immunohistochemistry protocols direct6
Immunohistochemistry protocols indirect7
Immunohistochemistry interpretation of results and troubleshooting8
Immunofluorescence tissue preparation , staining and interpretation of result troubleshooting10
Neuroendocrine techniques11
Neuropathology techniques12
Electron microscope structure, tissue processing, staining ,operation 13
Photomicrography14


Title of the course:        Cytogenetic and  molecular pathology

Intended term:     8

Course duration: 14 weeks.

Study hours per week: (2 theory + 2 practical).

Credit hours: 4

Pre-requisite course:

         Basic pathology, systemic pathology and Molecular biology

Course description:

              During this course student well study theoretical and practical bases of classical, clinical and molecular cytogenetic and their application in medicine molecular pathology technologies and their application in medicine of specific disease beside to studying cancer biology and cancer genetics.

Specific objective:

1- Definition and importance of cytogenetic Human genetics; an introduction to the subject, Terminology, classifications and nomenclature of human Chromosomes

  1. Methods for Karyotyping and analysis of chromosomal abnormalities
  2. Characterization of human chromosomes by various banding techniques. Translocation.
  3. Cell division, cell cycle and alterations in cell cycle checkpoints in cancer cells
  4. Gametogenesis and Cytogenetic of infertility
  5. Cancer cytogenetics: Common chromosomal observations in cancer, mechanisms of their production and of  Oncogenes.
  6. Key aspects of apoptosis and its misregulation in cancers , Apoptosis and Cell Senescence
  7.  Regulation of epithelial cell-cell adhesion by tumor suppressors and proto-oncogenes. Dysregulation of this process in invasion and metastasis of cancer cells.
  8. Outline current understanding of the properties of cancer stem cells and the implications for disease progression. Potential application of cancer vaccines to disease therapy.
  9. Cellular and molecular regulation of tissue fibrosis, mechanisms of persistence and implications for survival and therapy.
  10.  Blotting Techniques: Methodology and Applications
  11.  In-situ Hybridization in Histopathology, The In-situ Polymerase Chain Reaction Comparative Genomic Hybridization in Pathology
  1.  Flow cytometry methods , DNA Flow Cytometry , Application of FISH and microarray in cytogenetics .

1- Lectures:

LecturesWeeks
 Introduction to cytogenetic: Historical background, definition, importance of cytogenetic   , Terminology.1
Chromosome: structure, function, classification and nomenclature, replication, segregation and the centersome.2
Chromosomal abnormalities: numerical ,structural , in clinical syndromes associated with cytogenetic disorders ,Mechanisms of structural Abnormalities ,  Sex chromosome abnormalities  3
Methods for Karyotyping types and analysis of chromosomal abnormalities, Characterization of human chromosomes by various banding techniques and Translocation4
Gametogenesis and Cytogenetics of infertility, prenatal, spontaneous abortion, chromosomal instability5
Cancer cytogenetics: Common chromosomal observations in cancer, mechanisms of their production and of  Oncogenes, Cytogenetics of Cancer (Solid Tumors)6
Gene expression and Cell division, cell cycle , alterations in cell cycle checkpoints in cancer cells Key aspects of apoptosis and its misregulation in cancers , Apoptosis and Cell Senesce7
Dysregulation of epithelial cell-cell adhesion by tumor, properties of cancer stem cells and the implications for disease progression. Potential application of cancer vaccines to disease therapy8
Molecular pathology techniques overview, PCR types and blotting techniques    (Methodology and Applications).9
In-situ Hybridization in Histopathology,10
The In-situ Polymerase Chain ReactionComparative Genomic Hybridization in Pathology11
Molecular cytogenetics methods-FISH12
Application of FISH and In-situ Hybridization13
Flow cytometry methods , DNA Flow Cytometry ,14

Practical

PracticalWeeks
Sex chromatin identification1
Sample collection for cytogenetic tests2
Culture of bone marrow, peripheral blood lymphocytes, solid tumors, skin fibroblast, etc.  Direct preparations from tumor material3
Methods for Karyotyping and analysis of chromosomal abnormalities4
Characterization of human chromosomes by various banding techniques5
PCR techniques6
Blotting techniques7
In situ hybridization8
FISH9


 Diagnostic Clinical chemistry

Course Title : special of clinical chemistry(A) :

Course Smester : 7

Credit hours : 4

Prerequisites :study the following course :

  1. General and analytical chemistry
  2. Biochemistry
  3. Introduction to clinical chemistry
  4. Physiology

Course duration 🙁 14 -16 week)

Course description :

Enzyme assay, interpretation of enzyme results , hormonal transduction , hormonal assay , tumor markers ,toxicology, calculi,Therapeutic drug monitoring, Automation in clinical chemistry, Electrophoresis, Chromatography, Flame photometry, Spectrophotometry, Electrochemistry, Immunoassays and nucleic acid probe techniques

Course objectives :

By the end of this course , the students should able to :

  1. Define enzymes and hormonal assay .
  2. Discuss hormonal transduction & tumor markers.
  3. Classify enzymes , hormonal and lipoproteins.

Course contents (topics):

Theory :

  1. Enzymes assay (Enzyme Kinetics and Spectrophotometer ).
  2. Interpretation of enzymes results( Measurement and Calculation of enzyme Activity and reference Value for Enzyme ).
  3. Hormonal transduction (Other Hormones of Clinical Interest and Entopic Hormone Production ).
  4. Hormonal assay( Fluorescent technique , High-performance Liquid Chromatography and Colorimetry ).
  5. Therapeutic drug monitoring 🙁 Routes of administration , absorption , free versus bound drugs , drug distribution , drug elimination , pharmacokinetics ,sample collection , cardioactive drugs , antibiotics , antibiotic drugs ,psychoactive drugs , bronchoactive drugs , immunosppressive drugs , antieoplastics).
  6. Toxicology : ( Exposure to toxins , routes of exposure , dose-response relationship , analysis of toxic agents , toxicology of specific agents , toxicology of therapeutic drugs , toxicology of drugs of abuse).
  7. Circulation tumor markers : ( Basic concepts , specificity and sensitivity , clinical utilities of tumor markers , types of tumor markers , recommendations for test ordering , frequently ordered  tumor markers ).
  8. Automation in clinical chemistry( History of automated analyzer  , basic approaches to automation and type of automation ( centrifugal & discrete & continuous flow ).
  9. Electrophoresis( Procedure , support materials , treatment & application of sample , detection & quantitation and capillary electrophoresis ).
  10. Chromatography ( Mode of separation , chromatographic procedures and type of chromatography ( high-performance liquid chromatography & gas chromatography ).
  11. Flame photometry( Principle , component and application of flame photometry ).
  12. Spectrophotometry( Beer’s law , spectrophotometry  instruments , components of spectrophotometer ).
  13. Electrochemistry : ( Galvanic and electrolytic cells , ion selective electrodes , pH met electrodes , gas sensing electrodes ) .
  14. Immunoassays and nucleic acid probe techniques : (Immunoassays , nucleic acid probes ).
  15. Calculi ( formation, types and analysis|)

Practical:-

  1. Automation techniques.
  2. Spectrophotometry.
  3. Chromatography techniques.
  4. Ion selective electrodes and blood gas analyzer.
  5. Immunoassays techniques.
  6. Electrophoresis techniques.
  7. Flame photometry.
  8. Estimation of Vitamin B12.
  9. Estimation of folate.
  10. Stone analysis.
  11. Selenium.
  12. Tumor markers (PSA, HCG, CEA, CA 125, CA 9 – 19).

Course Title : special of clinical chemistry (B):

Course Smester : 8

Credit hours : 4

Prerequisites :study the following course :

  1. General and analytical chemistry
  2. Biochemistry
  3. Introduction to clinical chemistry
  4. Physiology

Course duration :2( 14 -16 week)

Course description :

Monitoring and complication of diabetes mellitus , evaluation of kidney diseases , physiological and pathological jaundice , plasma lipoproteins, globulins abnormalities , GIT disorders , minerals and trace elements and inborn error of metabolism, vitamins,Pancreatic function,Cardiac function, Clinical chemistry and geriatric patients, Pediatric clinical chemistry, Prophyrins and hemoglobin, Point – of – care testing ,Requesting tests, Interpreting results Quality control.

Course objectives: ?

By the end of this course , the students should able to :

  1. Quality control
  2. Discuss diabetes complications and jaundice .
  3. Discuss kidney diseases , globulin abnormalities , gastrointestinal tract (GIT) disorders and inborn error of metabolism .
  4. Explain minerals and trace elements .

Course contents (topics):

Theory :

  1. Quality control: (Control sera (types preparation),Control chart(shewart chart, cusum chart, leveteninig chart),West gard rules, Method validation (characterization of validation parameters),Recovery experiment, Selectivity, Linearity, Limit of detection, limit quantitation Interference experiment, Replication experiment, Reportable range, Comperesion of method, Laboratory accreditation)
  2. Monitoring and complication of diabetes mellitus( Self monitoring of Blood Glucose (2-hour post prandial tests , Glycosylated Hemoglobin ) and complications (ketoses and diabetic neuropathy and neuropathy ).
  3. Kidney disease evaluation( Laboratory diagnosis of glomerular and tubular diseases ).
  4. Physiological and pathological jaundice (Hyper and Hypobilirubinemia , Neonatal jaundice , reye’s syndrome and gilbert syndrome).
  5. Plasma lipoproteins (Lipoprotein distribution in the population , diseases related (Arteriosclerosis ), Lp(a) Elevation , Hyperlipoproteinemia and Hyperlipoproteinemia).
  6. GIT disorders (Physiology , Biochemistry and Laboratory Diagnosis of Gastric and Intestinal Secretion . Malabsorption and Occult Blood ).
  7. Globulins abnormalities (Paraglobuinemia (Alpha 1 antitrypsin )).
  8. Minerals and trace elements ( Functions , abnormalities and laboratory diagnosis of ( Iron , copper Zinc , Cobalt chromium , fluorine , manganese , selenium , and molybdenum ).
  9. Inborn error of metabolism( metabolic screening procedures and laboratory diagnosis of metabolic disorders ).
  10. Pancreatic function( physiology of pancreatic function , diseases of the pancreas , tests , of pancreas function ).
  11. Cardiac function : (heart disease , congenital heart disease , congestive heart failure , acute coronary syndrome , infective heart disease , diagnosis of heart disease ).
  12. Vitamins : (Fat-soluble vitamins , water soluble vitamins , essential fatty acids , the malnutrition risk , nutritional assessment ).
  13. Clinical chemistry and geriatric patients :  ( The impact of geriatric patients on the clinical laboratory , theories of aging , biochemical and physiologic changes of aging , clinical chemistry results and aging ).
  14. Pediatric clinical chemistry : ( Developmental changes from neonate to adult , phlebotomy and choice of instrumentation for pediatric samples , point-of-care analysis in pediatrics ).
  15. Prophyrins and hemoglobin : (Prophyrins , hemoglobin , myoglobin ).
  16. Point – of – care testing : ( Administration and structure , communication , proficiency testing , POC applications ) .
  17. Requesting tests .
  18. Interpreting results .

Practical:-

  1. Kidney function test
  2. Liver function test
  3. Diabetic profile
  4. Cardiac function( CKmb, troponin)
  5. Pediatric clinical chemistry…
  6. Vitamins evaluations.(B12, folic acid)
  7. Zinc in body fluids.
  8. Iron estimation.
  9. Porphyrin in blood.
  10. Uroporphyrin in urine.
  11. Co proporphyrin in stool.
  12. Lead and Mercury.
  13. Control sera (types preparation)
  14. Control chart(shewart chart, cusum chart, leveteninig chart)
  15. West gard rules
  16. Method validation (characterization of validation parameters)
  17. Recovery experiment
  18. Selectivity
  19. Linearity
  20. Limit of detection, limit quantitation
  21. Interference experiment
  22. Replication experiment
  23. Reportable range
  24. Comperesion of method
  25. Laboratory accreditation
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